PMID- 10023622
OWN - NLM
STAT- MEDLINE
DCOM- 19990308
LR  - 20190720
IS  - 0021-9673 (Print)
IS  - 0021-9673 (Linking)
VI  - 830
IP  - 1
DP  - 1999 Jan 8
TI  - Liquid chromatography-electrospray mass spectrometry multi-residue determination 
      of pesticides in apples and pears.
PG  - 135-43
AB  - This paper describes a rapid, specific and sensitive multi-residue method for the 
      routine quantitative analysis of pesticides of several classes used for the 
      treatment of apples and pears, down to their respective maximum residue limits 
      (MRLs). It involves a rapid extraction procedure and liquid chromatography 
      coupled to electrospray mass selective detection. Seven pesticides were extracted 
      at pH 4.5 with a mixture of acetone-dichloromethane-hexane (50:20:30, v/v/v). 
      Ionization was performed at atmospheric pressure in an electrospray-type source 
      and detection was carried out using the selected ion monitoring (SIM) mode. 
      Extraction recoveries were between 55 and 98% except for methylthiophanate (< 
      20%). Limits of detection (LODs) and limits of quantitation (LOQs) ranged, 
      respectively, from 0.01 to 0.02 mg/kg and from 0.02 to 0.05 mg/kg, with relative 
      standard deviation (R.S.D.) less than 19%. An excellent linearity was observed 
      for LOQs up to 5 mg/kg. Intermediate ("inter-assay") precision and accuracy were 
      satisfactory. The method was applied to many fruit samples intended for 
      commercialization.
FAU - Lacassie, E
AU  - Lacassie E
AD  - Department of Pharmacology and Toxicology, University Hospital, Limoges, France.
FAU - Dreyfuss, M F
AU  - Dreyfuss MF
FAU - Daguet, J L
AU  - Daguet JL
FAU - Vignaud, M
AU  - Vignaud M
FAU - Marquet, P
AU  - Marquet P
FAU - Lachatre, G
AU  - Lachatre G
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Pesticide Residues)
SB  - IM
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Chromatography, Thin Layer
MH  - Fruit/*chemistry
MH  - Mass Spectrometry/*methods
MH  - Pesticide Residues/*analysis
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
EDAT- 1999/02/19 00:00
MHDA- 1999/02/19 00:01
CRDT- 1999/02/19 00:00
PHST- 1999/02/19 00:00 [pubmed]
PHST- 1999/02/19 00:01 [medline]
PHST- 1999/02/19 00:00 [entrez]
AID - S0021-9673(98)00871-1 [pii]
AID - 10.1016/s0021-9673(98)00871-1 [doi]
PST - ppublish
SO  - J Chromatogr A. 1999 Jan 8;830(1):135-43. doi: 10.1016/s0021-9673(98)00871-1.