PMID- 10024804 OWN - NLM STAT- MEDLINE DCOM- 19990316 LR - 20061115 IS - 0021-5252 (Print) IS - 0021-5252 (Linking) VI - 52 IP - 1 DP - 1999 Jan TI - [Effects of coronary artery bypass surgery on the stunned and hibernating myocardium in the cases with depressed left ventricular function]. PG - 59-63 AB - Chronic left ventricular (LV) dysfunction may result from irreversible damage (cell death), stunned myocardium (ST), or hibernating myocardium (HB). However, both of ST and HB are expected to be reversible. In this report, the effects of coronary artery bypass grafting on the regions of ST and HB were evaluated in 37 patients with less than 40% of LV ejection fraction. The patients were divided into two groups. Group I consisted of the patients whose postoperative LV ejection fraction rose by more than 10% compared to the preoperative value. Group II included the remaining patients with no significant improvement. After successful revascularization, 61% of HB changed to ST and 52% of ST to normal in group I. These changes were significant in comparison with group II because 48% of HB and 83% of ST in group II remained unchanged. Immediate or rapid recovery of HB hardly occurred in both of the groups. To recover normal function, HB may pass through a stage of ST on reperfusion. On the other hand, it is difficult to determine whether HB and ST with no significant changes after reperfusion are irreversibly damaged or reversible and take time to return to normal. FAU - Konishi, Y AU - Konishi Y AD - Cardiovascular Surgery, Japanese Red Cross Society Wakayama Medical Center, Japan. FAU - Matsumoto, M AU - Matsumoto M FAU - Miwa, S AU - Miwa S FAU - Minakata, K AU - Minakata K FAU - Nonaka, M AU - Nonaka M FAU - Yamada, N AU - Yamada N LA - jpn PT - English Abstract PT - Journal Article PL - Japan TA - Kyobu Geka JT - Kyobu geka. The Japanese journal of thoracic surgery JID - 0413533 SB - IM MH - Aged MH - *Coronary Artery Bypass MH - Coronary Circulation MH - Female MH - Humans MH - Male MH - Middle Aged MH - Myocardial Stunning/physiopathology/*surgery MH - Ventricular Dysfunction, Left/physiopathology/*surgery EDAT- 1999/02/20 00:00 MHDA- 1999/02/20 00:01 CRDT- 1999/02/20 00:00 PHST- 1999/02/20 00:00 [pubmed] PHST- 1999/02/20 00:01 [medline] PHST- 1999/02/20 00:00 [entrez] PST - ppublish SO - Kyobu Geka. 1999 Jan;52(1):59-63.