PMID- 10024956
OWN - NLM
STAT- MEDLINE
DCOM- 19990415
LR  - 20161124
IS  - 0942-2056 (Print)
IS  - 0942-2056 (Linking)
VI  - 7
IP  - 1
DP  - 1999
TI  - Early histologic appearance of human patellar tendon autografts used for anterior 
      cruciate ligament reconstruction.
PG  - 9-14
AB  - Nine patients underwent second-look arthroscopy and biopsy between 3 and 8 weeks 
      after anterior cruciate ligament (ACL) reconstruction using autogenous patellar 
      tendon. All nine biopsies were taken from the central region of the graft. Every 
      biopsy revealed viable cells in two different patterns. As early as 3 weeks after 
      ACL reconstruction, there were areas that were very similar to patellar tendon 
      control specimens with low nuclear counts, mature collagen, and elongated, 
      metabolically quiescent nuclear morphology. Other areas were hypercellular and 
      associated intimately with neovascular invasion. Vascularity of the grafts was 
      present as early as 3 weeks after reconstruction and increased in prevalence over 
      the next 5 weeks. All specimens had areas of acellularity and degeneration. From 
      these data, the authors conclude that the transplantation of nonvascularized, 
      autogenous patellar tendon is characterized by early viability of the graft both 
      from original fibroblasts and by new cells that arise from neovascularity that is 
      present as early as 3 weeks after ACL reconstruction.
FAU - Rougraff, B T
AU  - Rougraff BT
AD  - Department of Orthopaedics and Pathology, Indiana University School of Medicine, 
      Indianapolis 46202-5111, USA.
FAU - Shelbourne, K D
AU  - Shelbourne KD
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Knee Surg Sports Traumatol Arthrosc
JT  - Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
JID - 9314730
SB  - IM
MH  - Anterior Cruciate Ligament/*surgery
MH  - *Anterior Cruciate Ligament Injuries
MH  - Biopsy
MH  - Humans
MH  - Knee Injuries/pathology/*surgery
MH  - Postoperative Period
MH  - Tendons/*pathology/*transplantation
EDAT- 1999/02/20 00:00
MHDA- 1999/02/20 00:01
CRDT- 1999/02/20 00:00
PHST- 1999/02/20 00:00 [pubmed]
PHST- 1999/02/20 00:01 [medline]
PHST- 1999/02/20 00:00 [entrez]
AID - 10.1007/s001670050113 [pii]
AID - 10.1007/s001670050113 [doi]
PST - ppublish
SO  - Knee Surg Sports Traumatol Arthrosc. 1999;7(1):9-14. doi: 10.1007/s001670050113.