PMID- 10036339 OWN - NLM STAT- MEDLINE DCOM- 19990405 LR - 20191102 IS - 1050-1606 (Print) IS - 1050-1606 (Linking) VI - 9 IP - 1 DP - 1999 Mar TI - Glucose ingestion matched with total carbohydrate utilization attenuates hypoglycemia during exercise in adolescents with IDDM. PG - 24-34 AB - There are currently no guidelines regarding the carbohydrate (CHO) dosage required to prevent exercise-induced hypoglycemia in children with insulin-dependent diabetes mellitus (IDDM). To prevent hypoglycemia by matching glucose ingestion with total-CHO utilization, 20 adolescents with IDDM attended 2 trials: control (CT; drinking water) and glucose (GT; drinking 6-8% glucose). Participants performed 60 min of moderate-intensity cycling 100 min after insulin injection and breakfast. CT's total-CHO utilization during exercise was determined using indirect calorimetry. In GT, participants ingested glucose in the amount equal to total CHO utilization in the CT. A total of 9 participants had BG < 4.0 mmol/L in CT compared to 3 in GT (p < .05). In conclusion, glucose ingestion equal to total-CHO utilization attenuates the drop in blood glucose and reduces the likelihood of hypoglycemia during exercise in adolescents with IDDM. FAU - Riddell, M C AU - Riddell MC AD - Children's Exercise and Nutrition Centre, McMaster University, Hamilton, ON Canada. FAU - Bar-Or, O AU - Bar-Or O FAU - Ayub, B V AU - Ayub BV FAU - Calvert, R E AU - Calvert RE FAU - Heigenhauser, G J AU - Heigenhauser GJ LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Int J Sport Nutr JT - International journal of sport nutrition JID - 9307702 RN - 0 (Blood Glucose) RN - 0 (Dietary Carbohydrates) RN - 0 (Insulin) RN - IY9XDZ35W2 (Glucose) SB - IM MH - Adolescent MH - Analysis of Variance MH - Blood Glucose/analysis MH - Calorimetry, Indirect MH - Diabetes Mellitus, Type 1/*metabolism/prevention & control MH - Dietary Carbohydrates/*administration & dosage/metabolism MH - Exercise Test MH - Female MH - Glucose/*administration & dosage/metabolism MH - Humans MH - Hypoglycemia/*prevention & control MH - Insulin/therapeutic use MH - Male MH - Oxygen Consumption MH - Physical Exertion/*physiology MH - Respiration EDAT- 1999/02/26 00:00 MHDA- 1999/02/26 00:01 CRDT- 1999/02/26 00:00 PHST- 1999/02/26 00:00 [pubmed] PHST- 1999/02/26 00:01 [medline] PHST- 1999/02/26 00:00 [entrez] AID - 10.1123/ijsn.9.1.24 [doi] PST - ppublish SO - Int J Sport Nutr. 1999 Mar;9(1):24-34. doi: 10.1123/ijsn.9.1.24.