PMID- 10036957
OWN - NLM
STAT- MEDLINE
DCOM- 19990416
LR  - 20201209
IS  - 0047-1852 (Print)
IS  - 0047-1852 (Linking)
VI  - 57
IP  - 1
DP  - 1999 Jan
TI  - [Effects of Helicobacter pylori eradication therapy on the healing process of 
      peptic ulcers].
PG  - 167-72
AB  - The advent of H2-receptor antagonists (H2RA) and proton pump inhibitors (PPI) has 
      particularly revolutionized the treatment of peptic ulcer disease. Most cases can 
      now be successfully controlled by medical treatment with H2RA and PPI, but a high 
      rate of ulcer recurrence remains an important problem. The quality of ulcer 
      healing (QOUH) has therefore received increasing attention, and various 
      investigators have attempted to define the conditions required for nonrecurrence. 
      Ulcer scars with a good QOUH are considered to have a very low risk of 
      recurrence. Recent studies have confirmed that recurrence of peptic ulcer can be 
      suppressed markedly by eradication of Helicobacter pylori (H. p). Moreover, 
      various types of endoscopic examinations (conventional observation, dye-contrast 
      endoscopy, magnifying endoscopy, endoscopic ultrasonography, pharmacoendoscopy) 
      have confirmed that the QOUH after eradication of H. p is better than that after 
      conventional anti-ulcer therapy. H. p eradication therapy may become treatment of 
      first choice for peptic ulcers.
FAU - Imaizumi, H
AU  - Imaizumi H
AD  - Department of Internal Medicine, Kitasato University School of Medicine.
FAU - Koizumi, W
AU  - Koizumi W
FAU - Nakai, H
AU  - Nakai H
FAU - Tanabe, S
AU  - Tanabe S
FAU - Ohida, M
AU  - Ohida M
FAU - Saigenji, K
AU  - Saigenji K
LA  - jpn
PT  - Journal Article
PT  - Review
PL  - Japan
TA  - Nihon Rinsho
JT  - Nihon rinsho. Japanese journal of clinical medicine
JID - 0420546
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Anti-Ulcer Agents)
RN  - 0 (Histamine H2 Antagonists)
RN  - 0 (Proton Pump Inhibitors)
RN  - KG60484QX9 (Omeprazole)
SB  - IM
MH  - Anti-Bacterial Agents
MH  - Anti-Ulcer Agents/therapeutic use
MH  - Drug Therapy, Combination/therapeutic use
MH  - Helicobacter Infections/drug therapy/*pathology
MH  - *Helicobacter pylori
MH  - Histamine H2 Antagonists/therapeutic use
MH  - Humans
MH  - Omeprazole/therapeutic use
MH  - Peptic Ulcer/drug therapy/*pathology
MH  - Proton Pump Inhibitors
MH  - Secondary Prevention
RF  - 14
EDAT- 1999/02/26 00:00
MHDA- 1999/02/26 00:01
CRDT- 1999/02/26 00:00
PHST- 1999/02/26 00:00 [pubmed]
PHST- 1999/02/26 00:01 [medline]
PHST- 1999/02/26 00:00 [entrez]
PST - ppublish
SO  - Nihon Rinsho. 1999 Jan;57(1):167-72.