PMID- 10073406
OWN - NLM
STAT- MEDLINE
DCOM- 19990420
LR  - 20051117
IS  - 1081-0943 (Print)
IS  - 1081-0943 (Linking)
VI  - 17
IP  - 1
DP  - 1999 Feb
TI  - The role of radiation therapy in the management of Wilms' tumor.
PG  - 46-54
AB  - Since the early decades of this century, radiation therapy has played an 
      important role in the management of Wilms' tumor. Although in prior years the 
      high radiation doses and eccentric field arrangements used in treatment were 
      responsible for significant late toxicity, examination of long-term survivors and 
      the important information obtained from the National Wilms' Tumor Studies (NWTS) 
      and Societe Internationale d'Oncologie Pediatrique studies have now allowed us to 
      tailor radiation fields and doses to provide high levels of local tumor control 
      with minimal late effects. At present, most patients with NWTS stage III and 
      stage IV tumors are offered radiotherapy as an integral component of their cancer 
      management. Attempts to further refine selection criteria defining those patient 
      groups who will benefit from radiation therapy are ongoing.
FAU - Davies-Johns, T
AU  - Davies-Johns T
AD  - Department of Radiation Oncology, Cleveland Clinic Foundation, OH 44195, USA.
FAU - Chidel, M
AU  - Chidel M
FAU - Macklis, R M
AU  - Macklis RM
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Semin Urol Oncol
JT  - Seminars in urologic oncology
JID - 9514993
SB  - IM
MH  - Child
MH  - Combined Modality Therapy
MH  - Humans
MH  - Kidney Neoplasms/mortality/*radiotherapy
MH  - Radiotherapy/adverse effects
MH  - Radiotherapy Dosage
MH  - Survival Rate
MH  - Wilms Tumor/mortality/*radiotherapy/secondary
EDAT- 1999/03/12 00:00
MHDA- 1999/03/12 00:01
CRDT- 1999/03/12 00:00
PHST- 1999/03/12 00:00 [pubmed]
PHST- 1999/03/12 00:01 [medline]
PHST- 1999/03/12 00:00 [entrez]
PST - ppublish
SO  - Semin Urol Oncol. 1999 Feb;17(1):46-54.