PMID- 10074605 OWN - NLM STAT- MEDLINE DCOM- 19990318 LR - 20190815 IS - 1523-6838 (Electronic) IS - 0272-6386 (Linking) VI - 33 IP - 2 DP - 1999 Feb TI - Acute renal failure from multiple myeloma precipitated by ACE inhibitors. PG - E5 AB - Renal failure in multiple myeloma can be precipitated during hemodynamic perturbances of renal blood flow, as seen secondary to volume depletion, radiocontrast dye, and nonsteroidal anti-inflammatory agents. We report two cases of acute renal failure that developed suddenly after initiation of angiotensin-converting enzyme (ACE) inhibitor, both with biopsy-proven cast nephropathy. ACE inhibitors may contribute to the intratubular light chain cast formation and acute "myeloma kidney" in susceptible patients. FAU - Rabb, H AU - Rabb H AD - Division of Nephrology, Hennepin County Medical Center, Minneapolis, MN 55415, USA. rabbx003@tc.umn.edu FAU - Gunasekaran, H AU - Gunasekaran H FAU - Gunasekaran, S AU - Gunasekaran S FAU - Saba, S R AU - Saba SR LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Am J Kidney Dis JT - American journal of kidney diseases : the official journal of the National Kidney Foundation JID - 8110075 RN - 0 (Angiotensin-Converting Enzyme Inhibitors) RN - 69PN84IO1A (Enalapril) RN - 9G64RSX1XD (Captopril) SB - IM MH - Acute Kidney Injury/*etiology MH - Aged MH - Angiotensin-Converting Enzyme Inhibitors/*adverse effects MH - Back Pain/complications/drug therapy MH - Captopril/*adverse effects MH - Diabetes Mellitus, Type 1/complications MH - Enalapril/*adverse effects MH - Humans MH - Hypertension/complications/drug therapy MH - Male MH - Multiple Myeloma/complications/*drug therapy EDAT- 1999/03/13 00:00 MHDA- 1999/03/13 00:01 CRDT- 1999/03/13 00:00 PHST- 1999/03/13 00:00 [pubmed] PHST- 1999/03/13 00:01 [medline] PHST- 1999/03/13 00:00 [entrez] AID - S0272-6386(99)70326-4 [pii] AID - 10.1016/s0272-6386(99)70326-4 [doi] PST - ppublish SO - Am J Kidney Dis. 1999 Feb;33(2):E5. doi: 10.1016/s0272-6386(99)70326-4.