PMID- 10080038 OWN - NLM STAT- MEDLINE DCOM- 19990806 LR - 20190905 IS - 0376-8716 (Print) IS - 0376-8716 (Linking) VI - 53 IP - 2 DP - 1999 Jan 7 TI - Ecstasy (MDMA) dependence. PG - 121-4 AB - Methylenedioxymethamphetamine (MDMA) is generally described as non-addictive. However, this report describes three cases in which criteria for dependence were met. A wider understanding that MDMA can be addictive in rare cases is important as very heavy use may cause lasting neuronal changes. This risk could be reduced with effective identification and treatment of dependent persons. In one case dependence was linked with self-medication of post-traumatic stress disorder (PTSD). FAU - Jansen, K L AU - Jansen KL AD - The Maudsley Hospital, Denmark Hill, London, UK. k@btinternet.com LA - eng PT - Case Reports PT - Journal Article PL - Ireland TA - Drug Alcohol Depend JT - Drug and alcohol dependence JID - 7513587 RN - 0 (Hallucinogens) RN - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine) SB - IM MH - Adult MH - Hallucinogens/*adverse effects/therapeutic use MH - Humans MH - Male MH - N-Methyl-3,4-methylenedioxyamphetamine/*adverse effects/therapeutic use MH - Seizures/chemically induced MH - Self Medication MH - Stress Disorders, Post-Traumatic/drug therapy MH - Substance-Related Disorders/*diagnosis EDAT- 1999/03/18 00:00 MHDA- 1999/03/18 00:01 CRDT- 1999/03/18 00:00 PHST- 1999/03/18 00:00 [pubmed] PHST- 1999/03/18 00:01 [medline] PHST- 1999/03/18 00:00 [entrez] AID - S0376871698001112 [pii] AID - 10.1016/s0376-8716(98)00111-2 [doi] PST - ppublish SO - Drug Alcohol Depend. 1999 Jan 7;53(2):121-4. doi: 10.1016/s0376-8716(98)00111-2.