PMID- 10084716 OWN - NLM STAT- MEDLINE DCOM- 19990525 LR - 20191103 IS - 0928-4257 (Print) IS - 0928-4257 (Linking) VI - 93 IP - 1-2 DP - 1999 Jan-Apr TI - An influence of afterhyperpolarization on the pattern of motoneuronal rhythmic activity. PG - 125-33 AB - Motoneuronal spike trains were generated according to a simple model assuming algebraical summation of the afterhyperpolarization (AHP) curve and noisy synaptic inflow. An influence of various model parameters on the relationship between standard deviation (SD), sigma, of interspike intervals (ISIs) and their mean value, Tm, was studied. A typical sigma(Tm) relationship resembled those obtained experimentally and consisted of two parts: a short-interval part with constant sigma and a long-interval part where sigma increased linearly with increasing ISI. It is concluded that the placement of the range of transition between short- and long-interval parts of the plot depends on the properties of the motoneuron and not on those of the synaptic inflow. The break-point interval of the plot is correlated with the AHP duration but is shorter than it. Further, not only are the curves for shorter AHP durations shifted towards shorter ISIs, but they also have lower SDs at their short-interval parts. FAU - Piotrkiewicz, M AU - Piotrkiewicz M AD - Bionics Department, Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - France TA - J Physiol Paris JT - Journal of physiology, Paris JID - 9309351 SB - IM MH - Animals MH - Cats MH - Computer Simulation MH - Excitatory Postsynaptic Potentials/*physiology MH - Linear Models MH - Models, Neurological MH - Motor Neurons/*physiology MH - Stochastic Processes MH - Synaptic Transmission/*physiology EDAT- 1999/03/20 00:00 MHDA- 1999/03/20 00:01 CRDT- 1999/03/20 00:00 PHST- 1999/03/20 00:00 [pubmed] PHST- 1999/03/20 00:01 [medline] PHST- 1999/03/20 00:00 [entrez] AID - S0928-4257(99)80143-0 [pii] AID - 10.1016/s0928-4257(99)80143-0 [doi] PST - ppublish SO - J Physiol Paris. 1999 Jan-Apr;93(1-2):125-33. doi: 10.1016/s0928-4257(99)80143-0.