PMID- 10091522
OWN - NLM
STAT- MEDLINE
DCOM- 19990427
LR  - 20191210
IS  - 0870-2551 (Print)
IS  - 0870-2551 (Linking)
VI  - 18
IP  - 1
DP  - 1999 Jan
TI  - [Elective coronary angioplasty in acute coronary syndromes: early versus delayed 
      treatment].
PG  - 29-33
AB  - BACKGROUND: In patients with acute coronary syndromes (ACS) the optimal time 
      required to stabilize the patient before attempting coronary intervention (PTCA) 
      is uncertain. The recent use of newer devices and antiplatelet drugs allowed 
      earlier percutaneous intervention. OBJECTIVE: We examined the efficacy and safety 
      of coronary angioplasty in patients with ACS according to the period of 
      stabilization with medical therapy. METHODS: We included 83 patients, 15 female, 
      54 with unstable angina and 29 with non-ST elevation myocardial infarction. We 
      studied the rate of complications related to the procedure, the duration of CCU 
      and hospital stay according to the period of stabilization with medical therapy: 
      < 48 hours (early PTCA) and > or = 48 hours (delayed PTCA). RESULTS: No 
      significant differences were found between the two groups of patients with 
      respect to success rate (92% in early PTCA vs 98% in delayed PTCA), stents 
      implantation (74% vs 78%), use of abeiximab (42% vs 24%), abrupt closure during 
      procedure (3% vs 2%), infarct related procedure (0% vs 7%), re-PTCA (5% vs 7%) 
      and surgical revascularization (0% vs 2%). No deaths occurred, CCU stay (2.5 vs 
      6.7 days, p < 0.001) and hospital stay (4 vs 9.4 days, p = 0.001) were 
      significantly shorter in the group of early PTCA. CONCLUSIONS: In the present 
      group of patients with ACS, early coronary intervention was a safe procedure with 
      a shorter CCU and hospital stay compared with deferred PTCA.
FAU - Almeida, M
AU  - Almeida M
AD  - Servico de Cardiologia, Hospital de Santa Cruz, Carnaxide.
FAU - Ferreira, J
AU  - Ferreira J
FAU - Real, T
AU  - Real T
FAU - Machado, F
AU  - Machado F
FAU - Baptista, J
AU  - Baptista J
FAU - Palos, J
AU  - Palos J
FAU - Silva, A
AU  - Silva A
FAU - Seabra-Gomes, R
AU  - Seabra-Gomes R
LA  - por
PT  - Clinical Trial
PT  - Journal Article
TT  - Angioplastia coronaria electiva nos sindromas coronarios agudos: procedimento 
      precoce versus diferido.
PL  - Portugal
TA  - Rev Port Cardiol
JT  - Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de 
      Cardiologia = Portuguese journal of cardiology : an official journal of the 
      Portuguese Society of Cardiology
JID - 8710716
RN  - 0 (Antibodies, Monoclonal)
RN  - 0 (Immunoglobulin Fab Fragments)
RN  - X85G7936GV (Abciximab)
SB  - IM
MH  - Abciximab
MH  - Adult
MH  - Aged
MH  - Angina Pectoris/complications/surgery
MH  - *Angioplasty, Balloon, Coronary
MH  - Antibodies, Monoclonal/therapeutic use
MH  - Coronary Disease/*surgery
MH  - *Elective Surgical Procedures
MH  - Female
MH  - Humans
MH  - Immunoglobulin Fab Fragments/therapeutic use
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/complications/surgery
MH  - Outcome and Process Assessment, Health Care
MH  - Time Factors
EDAT- 1999/03/26 00:00
MHDA- 1999/03/26 00:01
CRDT- 1999/03/26 00:00
PHST- 1999/03/26 00:00 [pubmed]
PHST- 1999/03/26 00:01 [medline]
PHST- 1999/03/26 00:00 [entrez]
PST - ppublish
SO  - Rev Port Cardiol. 1999 Jan;18(1):29-33.