PMID- 10095105
OWN - NLM
STAT- MEDLINE
DCOM- 19990517
LR  - 20220310
IS  - 0378-1119 (Print)
IS  - 0378-1119 (Linking)
VI  - 229
IP  - 1-2
DP  - 1999 Mar 18
TI  - Organization of the gene for gelatin-binding protein (GBP28).
PG  - 67-73
AB  - GBP28 is a novel human plasma gelatin-binding protein that is encoded by apM1 
      mRNA, expressed specifically in adipose tissue. Three overlapping clones (two 
      lambda clones and one BAC clone) containing the human plasma gelatin-binding 
      protein (GBP28) gene were isolated and characterized. The GBP28 gene spans 16kb 
      and is composed of three exons from 18bp to 4277bp in size with consensus splice 
      sites. The sizes of the two introns were 0.8 and 12kb, respectively. The gene's 
      regulatory sequences contain putative promoter elements, but no typical TATA box. 
      The third exon of this gene contains a long 3'-untranslated sequence containing 
      three Alu repeats. The exon-intron organization of this gene was very similar to 
      that of obese gene, encoding leptin. We also report the chromosome mapping of 
      this gene by fluorescence in situ hybridization (FISH) using a genomic DNA 
      fragment as a probe. The GBP28 gene was located on human chromosome 3q27. The 
      nucleotide sequence data reported in this paper will appear in the 
      DDBJ/EMBL/GenBank nucleotide sequence databases with the accession numbers 
      ABO12163, ABO12164 or ABO12165.
FAU - Saito, K
AU  - Saito K
AD  - Department of Physiological Chemistry, School of Pharmaceutical Sciences, Showa 
      University, Tokyo, Japan.
FAU - Tobe, T
AU  - Tobe T
FAU - Minoshima, S
AU  - Minoshima S
FAU - Asakawa, S
AU  - Asakawa S
FAU - Sumiya, J
AU  - Sumiya J
FAU - Yoda, M
AU  - Yoda M
FAU - Nakano, Y
AU  - Nakano Y
FAU - Shimizu, N
AU  - Shimizu N
FAU - Tomita, M
AU  - Tomita M
LA  - eng
SI  - GENBANK/AB012163
SI  - GENBANK/AB012164
SI  - GENBANK/AB012165
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Gene
JT  - Gene
JID - 7706761
RN  - 0 (Adiponectin)
RN  - 0 (Carrier Proteins)
RN  - 0 (Intercellular Signaling Peptides and Proteins)
RN  - 0 (Leptin)
RN  - 0 (Proteins)
SB  - IM
MH  - Adiponectin
MH  - Alu Elements/genetics
MH  - Animals
MH  - Base Sequence
MH  - Carrier Proteins/*genetics
MH  - Chromosome Mapping
MH  - Chromosomes, Human, Pair 3/genetics
MH  - Cloning, Molecular
MH  - Exons/genetics
MH  - Guinea Pigs
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - *Intercellular Signaling Peptides and Proteins
MH  - Introns/genetics
MH  - Leptin
MH  - Molecular Sequence Data
MH  - Promoter Regions, Genetic/genetics
MH  - Proteins/genetics
EDAT- 1999/03/30 00:00
MHDA- 1999/03/30 00:01
CRDT- 1999/03/30 00:00
PHST- 1999/03/30 00:00 [pubmed]
PHST- 1999/03/30 00:01 [medline]
PHST- 1999/03/30 00:00 [entrez]
AID - S0378-1119(99)00041-4 [pii]
AID - 10.1016/s0378-1119(99)00041-4 [doi]
PST - ppublish
SO  - Gene. 1999 Mar 18;229(1-2):67-73. doi: 10.1016/s0378-1119(99)00041-4.