PMID- 10096738
OWN - NLM
STAT- MEDLINE
DCOM- 19990513
LR  - 20171006
IS  - 0386-300X (Print)
IS  - 0386-300X (Linking)
VI  - 53
IP  - 1
DP  - 1999 Feb
TI  - Suitable image parameters and analytical method for quantitatively measuring 
      cerebral blood flow volume with phase-contrast magnetic resonance imaging.
PG  - 45-53
AB  - The aim of this study was to determine suitable image parameters and an 
      analytical method for phase-contrast magnetic resonance imaging (PC-MRI) as a 
      means of measuring cerebral blood flow volume. This was done by constructing an 
      experimental model and applying the results to a clinical application. The 
      experimental model was constructed from the aorta of a bull and circulating 
      isotonic saline. The image parameters of PC-MRI (repetition time, flip angle, 
      matrix, velocity rate encoding, and the use of square pixels) were studied with 
      percent flow volume (the ratio of actual flow volume to measured flow volume). 
      The most suitable image parameters for accurate blood flow measurement were as 
      follows: repetition time, 50 msec; flip angle, 20 degrees; and a 512 x 256 matrix 
      without square pixels. Furthermore, velocity rate encoding should be set ranging 
      from the maximum flow velocity in the vessel to five times this value. The 
      correction in measuring blood flow was done with the intensity of the region of 
      interest established in the background. With these parameters for PC-MRI, percent 
      flow volume was greater than 90%. Using the image parameters for PC-MRI and the 
      analytical method described above, we evaluated cerebral blood flow volume in 12 
      patients with occlusive disease of the major cervical arteries. The results were 
      compared with conventional xenon computed tomography. The values found with both 
      methods showed good correlation. Thus, we concluded that PC-MRI was a noninvasive 
      method for evaluating cerebral blood flow in patients with occlusive disease of 
      the major cervical arteries.
FAU - Handa, H
AU  - Handa H
AD  - Department of Neurological Surgery, Okayama University Medical School, Japan.
FAU - Aihara, H
AU  - Aihara H
FAU - Kinoshita, K
AU  - Kinoshita K
FAU - Ohmoto, T
AU  - Ohmoto T
FAU - Ito, T
AU  - Ito T
FAU - Kinugasa, K
AU  - Kinugasa K
FAU - Kamata, I
AU  - Kamata I
FAU - Asari, S
AU  - Asari S
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PL  - Japan
TA  - Acta Med Okayama
JT  - Acta medica Okayama
JID - 0417611
SB  - IM
MH  - Adult
MH  - Aged
MH  - Animals
MH  - Blood Volume/*physiology
MH  - Carotid Stenosis/diagnosis/physiopathology
MH  - Cattle
MH  - Cerebrovascular Circulation/*physiology
MH  - Constriction, Pathologic/diagnosis/physiopathology
MH  - Female
MH  - Humans
MH  - Magnetic Resonance Imaging/*methods
MH  - Male
MH  - *Microscopy, Phase-Contrast
MH  - Middle Aged
MH  - Models, Cardiovascular
MH  - Vertebral Artery/pathology/physiopathology
EDAT- 1999/03/30 00:00
MHDA- 1999/03/30 00:01
CRDT- 1999/03/30 00:00
PHST- 1999/03/30 00:00 [pubmed]
PHST- 1999/03/30 00:01 [medline]
PHST- 1999/03/30 00:00 [entrez]
AID - 10.18926/AMO/31650 [doi]
PST - ppublish
SO  - Acta Med Okayama. 1999 Feb;53(1):45-53. doi: 10.18926/AMO/31650.