PMID- 10102347
OWN - NLM
STAT- MEDLINE
DCOM- 19990420
LR  - 20240103
IS  - 0022-4790 (Print)
IS  - 0022-4790 (Linking)
VI  - 70
IP  - 3
DP  - 1999 Mar
TI  - Basal cell carcinoma of the vulva.
PG  - 172-6
AB  - BACKGROUND AND OBJECTIVES: Vulvar basal cell carcinoma (BCC) accounts for 7% of 
      all vulvar cancers at two hospitals in the south of Israel. The purpose of this 
      study was to investigate the clinical findings, treatment and outcome of patients 
      with vulvar BCC treated at these institutions. METHODS: Data from the files of 
      eight patients with vulvar BCC who were managed at two regional hospitals in the 
      south of Israel (Soroka Medical Center, Beer-Sheva and Kaplan Hospital, Rehovot) 
      between January 1961 and December 1997 were evaluated. RESULTS: Mean age at 
      diagnosis was 70.5 years. A history of other primary cancers was encountered in 
      two patients. Prevailing presenting symptoms were vulvar lump, ulcer, itching, 
      and bleeding. The tumor was most often located on the labium major and its mean 
      size was 2.25 cm. Six patients had wide local excision, one had excisional 
      biopsy, and one had hemivulvectomy. Two patients developed local recurrence and 
      were treated by wide local reexcision and hemivulvectomy, respectively. At 
      follow-up, no patient developed regional and/or distant metastases, or died of 
      BCC. CONCLUSIONS: Vulvar BCC is characterized by an indolent behavior with a very 
      low propensity for metastatic spread. The treatment of choice is wide local 
      excision. Because of a substantial risk of local recurrence and high frequency of 
      other primary cancers, close long-term follow-up is essential.
FAU - Piura, B
AU  - Piura B
AD  - Department of Obstetrics and Gynecology, Soroka Medical Center and Faculty of 
      Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel. 
      piura@bgumail.bgu.ac.il
FAU - Rabinovich, A
AU  - Rabinovich A
FAU - Dgani, R
AU  - Dgani R
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PL  - United States
TA  - J Surg Oncol
JT  - Journal of surgical oncology
JID - 0222643
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Carcinoma, Basal Cell/pathology/*surgery
MH  - Disease-Free Survival
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Middle Aged
MH  - Neoplasm Recurrence, Local
MH  - Treatment Outcome
MH  - Vulvar Neoplasms/pathology/*surgery
EDAT- 1999/04/02 03:03
MHDA- 2000/06/20 09:00
CRDT- 1999/04/02 03:03
PHST- 1999/04/02 03:03 [pubmed]
PHST- 2000/06/20 09:00 [medline]
PHST- 1999/04/02 03:03 [entrez]
AID - 10.1002/(SICI)1096-9098(199903)70:3<172::AID-JSO5>3.0.CO;2-I [pii]
AID - 10.1002/(sici)1096-9098(199903)70:3<172::aid-jso5>3.0.co;2-i [doi]
PST - ppublish
SO  - J Surg Oncol. 1999 Mar;70(3):172-6. doi: 
      10.1002/(sici)1096-9098(199903)70:3<172::aid-jso5>3.0.co;2-i.