PMID- 10148567 OWN - NLM STAT- MEDLINE DCOM- 19930826 LR - 20131121 IS - 1050-6934 (Print) IS - 1050-6934 (Linking) VI - 3 IP - 1 DP - 1993 TI - Tissue response of apatite-filled resin cement and titanium-reinforced apatite dental implants in dogs. PG - 69-79 AB - Abutment and root portion divided two-piece dental implants were designed to modify the one-piece dense hydroxyapatite (D-HAP) implant. The initial placement of the root portion endosseously ensured an aseptic environment and physical stability for the implant during the bone healing period. The outer D-HAP shell of the root portion was fortified by an inner titanium cylinder and cemented with an adhesive resin cement containing 4-methacryloyoxyethyl trimellitate anhydride (4-META) and reinforced by fine apatite filler. Upon attaining integration of the bone and implant, the abutment was screwed and fixed into the screw hole of the root portion. The tissue response of both the apatite-filled resin cement and root portion of the two-piece implant was studied by animal canine experiments. Light and electron microscopic examination of specimens taken from experimental animal tissue showed bone contacted directly not only the exposed apatite filler at the surface of the apatite-filled resin cement, but also the resin portion. These findings of direct bone contact suggested that the tissue response of apatite-filled resin cement was approximately similar to the usual D-HAP. Because most of the surface of the outer D-HAP shell of the root portion came in contact with bone, it prevented the deposition of contamination on the D-HAP surface during the manufacturing procedures of the root portion. FAU - Ogiso, M AU - Ogiso M AD - Faculty of Dentistry, Tokyo Medical and Dental University, Japan. FAU - Tabata, T AU - Tabata T FAU - Nakabayashi, N AU - Nakabayashi N FAU - Yamashita, Y AU - Yamashita Y FAU - Borgese, D AU - Borgese D LA - eng PT - Journal Article PL - United States TA - J Long Term Eff Med Implants JT - Journal of long-term effects of medical implants JID - 9110830 RN - 0 (Dental Cements) RN - 0 (Dental Implants) RN - 0 (Hydroxyapatites) RN - 0 (Methacrylates) RN - D1JT611TNE (Titanium) MH - Animals MH - Calcification, Physiologic MH - *Dental Cements MH - *Dental Implants MH - Dogs MH - Evaluation Studies as Topic MH - Hydroxyapatites MH - Materials Testing MH - Methacrylates MH - Microscopy MH - Microscopy, Electron MH - Titanium MH - Wound Healing EDAT- 1992/12/09 00:00 MHDA- 1992/12/09 00:01 CRDT- 1992/12/09 00:00 PHST- 1992/12/09 00:00 [pubmed] PHST- 1992/12/09 00:01 [medline] PHST- 1992/12/09 00:00 [entrez] PST - ppublish SO - J Long Term Eff Med Implants. 1993;3(1):69-79.