PMID- 10155170 OWN - NLM STAT- MEDLINE DCOM- 19951101 LR - 20170214 IS - 0885-0666 (Print) IS - 0885-0666 (Linking) VI - 10 IP - 1 DP - 1995 Jan-Feb TI - Spinal aspergillus abscess in a patient with bronchocentric granulomatosis. PG - 45-8 AB - Aspergillus fumigatus hyphae is often found in the lung tissue of patients with bronchocentric granulomatosis (BCG). This organism is believed to be one agent responsible for inciting the hypersensitivity response and subsequent development of the characteristic pathology that defines BCG. The definitive etiology of this disease, however, remains conjectural. Corticosteroids represent the mainstay of therapy. The fungi recovered from patients with BCG are considered noninvasive; thus, the risk of fungal invasion secondary to steroid-induced immunosuppression is believed to be negligible. However, we report a case of spinal aspergillus abscess that developed in a patient with BCG subsequent to steroid therapy. This case also highlights the necessity for aggressive medical and neurosurgical intervention to avert the development of neurological sequelae. FAU - Collier, J AU - Collier J AD - Department of Medicine, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, CA, USA. FAU - Wolfe, R AU - Wolfe R FAU - Lerner, R AU - Lerner R FAU - Nathan, S AU - Nathan S FAU - Mohsenifar, Z AU - Mohsenifar Z LA - eng PT - Case Reports PT - Journal Article PL - United States TA - J Intensive Care Med JT - Journal of intensive care medicine JID - 8610344 RN - 0 (Adrenal Cortex Hormones) CIN - J Intensive Care Med. 1995 Jan-Feb;10(1):3-4. PMID: 10155168 MH - Abscess/*diagnosis/therapy MH - Adrenal Cortex Hormones/therapeutic use MH - Adult MH - Aspergillosis/*diagnosis/therapy MH - Aspergillosis, Allergic Bronchopulmonary/*complications/drug therapy MH - Combined Modality Therapy MH - Female MH - Granuloma/*complications/drug therapy MH - Humans MH - Lung Diseases/*complications/drug therapy MH - Spinal Diseases/diagnosis/therapy MH - *Thoracic Vertebrae EDAT- 1994/12/09 00:00 MHDA- 1994/12/09 00:01 CRDT- 1994/12/09 00:00 PHST- 1994/12/09 00:00 [pubmed] PHST- 1994/12/09 00:01 [medline] PHST- 1994/12/09 00:00 [entrez] AID - 10.1177/088506669501000106 [doi] PST - ppublish SO - J Intensive Care Med. 1995 Jan-Feb;10(1):45-8. doi: 10.1177/088506669501000106.