PMID- 10188753 OWN - NLM STAT- MEDLINE DCOM- 19990506 LR - 20190831 IS - 0195-9131 (Print) IS - 0195-9131 (Linking) VI - 31 IP - 3 DP - 1999 Mar TI - The effect of a preexercise meal on time to fatigue during prolonged cycling exercise. PG - 464-71 AB - PURPOSE AND METHODS: Seven subjects exercised to exhaustion on a bicycle ergometer at a workload corresponding to an intensity of 70% maximal oxygen uptake (VO2max). On one occasion (FED), subjects consumed a preexercise carbohydrate (CHO) containing breakfast (100 g CHO) 3 h before exercise. On the other occasion (FASTED), subjects exercised after an overnight fast. Exercise time to fatigue was significantly longer (P < 0.05) when subjects consumed the breakfast (136+/-14 min) compared with when they exercised in the fasted state (109+/-12 min). RESULTS: Pre- and post-exercise muscle glycogen concentrations, respiratory exchange ratio, carbohydrate and fat oxidation, and lactate and insulin concentrations were not significantly different between the two trials. Insulin concentrations decreased significantly (P < 0.05) from 4.7+/-0.05 microIU.mL(-1) to 2.8+/-0.4 microIU.mL(-1) in FED and from 6.6+/-0.6 microIU.mL(-1) to 3.7+/-0.6 microIU.mL(-1) in FASTED subjects and free fatty acid concentrations (FFA) increased significantly (P < 0.05) from 0.09+/-0.02 mmol.L(-1) to 1.4+/-0.6 mmol.L(-1) in FED and from 0.17+/-0.02 mmol.L(-) to 0.74+/-0.27 mmol.L(-1) in FASTED subjects over the duration of the trials. CONCLUSIONS: In conclusion, the important finding of this study is the increased time to fatigue when subjects ingested the CHO meal with no negative effects ascribed to increased insulin concentrations and decreased FFA concentrations after CHO ingestion. FAU - Schabort, E J AU - Schabort EJ AD - MRC/UCT Bioenergetics of Exercise Research Unit, Sports Science Institute of South Africa, Newlands. FAU - Bosch, A N AU - Bosch AN FAU - Weltan, S M AU - Weltan SM FAU - Noakes, T D AU - Noakes TD LA - eng PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PL - United States TA - Med Sci Sports Exerc JT - Medicine and science in sports and exercise JID - 8005433 RN - 0 (Blood Glucose) RN - 0 (Dietary Carbohydrates) RN - 0 (Fatty Acids, Nonesterified) RN - 0 (Insulin) RN - 33X04XA5AT (Lactic Acid) RN - 9005-79-2 (Glycogen) SB - IM MH - Adult MH - Bicycling/*physiology MH - Blood Glucose/metabolism MH - *Dietary Carbohydrates MH - *Eating MH - Exercise/*physiology MH - Fatty Acids, Nonesterified/blood MH - Glycogen/metabolism MH - Humans MH - Insulin/blood MH - Lactic Acid/blood MH - Male MH - Muscle, Skeletal/metabolism MH - Oxygen Consumption MH - Physical Endurance/*physiology MH - Respiration EDAT- 1999/04/03 00:00 MHDA- 1999/04/03 00:01 CRDT- 1999/04/03 00:00 PHST- 1999/04/03 00:00 [pubmed] PHST- 1999/04/03 00:01 [medline] PHST- 1999/04/03 00:00 [entrez] AID - 10.1097/00005768-199903000-00017 [doi] PST - ppublish SO - Med Sci Sports Exerc. 1999 Mar;31(3):464-71. doi: 10.1097/00005768-199903000-00017.