PMID- 10198616
OWN - NLM
STAT- MEDLINE
DCOM- 19990421
LR  - 20041117
IS  - 0165-4608 (Print)
IS  - 0165-4608 (Linking)
VI  - 110
IP  - 1
DP  - 1999 Apr
TI  - Dermatofibrosarcoma protuberans harboring t(9;22)(q32;q12.2).
PG  - 14-8
AB  - More than 20 cases of dermatofibrosarcoma protuberans (DFSP) exhibiting 
      chromosomal abnormalities have been reported. Approximately three fourths of 
      these tumors have harbored supernumerary ring chromosomes, which have been 
      suggested to be specific for this tumor. However, a small number of DFSPs with 
      translocations such as t(2;17), t(X;7), and t(17;22) have recently been reported. 
      We report a DFSP arising in a 23-year-old woman which unexpectedly exhibited the 
      balanced translocation, t(9;22)(q32;q12.2) as the only anomaly with G-band 
      technique. Dual-color fluorescence in situ hybridization (FISH) confirmed these 
      cytogenetic findings. Similar to that previously reported for DFSPs with 
      translocations, the present tumor also lacked ring chromosomes.
FAU - Sonobe, H
AU  - Sonobe H
AD  - Department of Pathology, Kochi Medical School, Japan.
FAU - Furihata, M
AU  - Furihata M
FAU - Iwata, J
AU  - Iwata J
FAU - Ohtsuki, Y
AU  - Ohtsuki Y
FAU - Chikazawa, M
AU  - Chikazawa M
FAU - Taguchi, T
AU  - Taguchi T
FAU - Shimizu, K
AU  - Shimizu K
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Cancer Genet Cytogenet
JT  - Cancer genetics and cytogenetics
JID - 7909240
SB  - IM
MH  - Adult
MH  - *Chromosomes, Human, Pair 22
MH  - *Chromosomes, Human, Pair 9
MH  - Dermatofibrosarcoma/*genetics
MH  - Female
MH  - Humans
MH  - Skin Neoplasms/*genetics
MH  - *Translocation, Genetic
EDAT- 1999/04/13 00:00
MHDA- 1999/04/13 00:01
CRDT- 1999/04/13 00:00
PHST- 1999/04/13 00:00 [pubmed]
PHST- 1999/04/13 00:01 [medline]
PHST- 1999/04/13 00:00 [entrez]
AID - S0165460898001836 [pii]
PST - ppublish
SO  - Cancer Genet Cytogenet. 1999 Apr;110(1):14-8.