PMID- 10206697
OWN - NLM
STAT- MEDLINE
DCOM- 19990413
LR  - 20200826
IS  - 1350-0872 (Print)
IS  - 1350-0872 (Linking)
VI  - 145 ( Pt 1)
DP  - 1999 Jan
TI  - Staphylococcus aureus expresses a cell surface protein that binds both IgG and 
      beta2-glycoprotein I.
PG  - 177-183
LID - 10.1099/13500872-145-1-177 [doi]
AB  - The existence of a second IgG-binding protein, protein Sbi, in Staphylococcus 
      aureus has been reported previously. Later data indicated that protein Sbi also 
      bound another serum component. This component has now been affinity-purified on 
      immobilized protein Sbi and identified as beta2-glycoprotein I (beta2-GPI), also 
      known as apolipoprotein H. The minimal beta2-GPI-binding domain was identified by 
      shotgun phage display and the binding was shown to be mediated by a region of 57 
      amino acids, clearly separated from the IgG-binding domain. It is also shown that 
      protein Sbi, and thus the beta2-GPI-binding activity, is expressed on the 
      staphylococcal cell surface at levels varying between strains.
FAU - Zhang, Lihong
AU  - Zhang L
FAU - Jacobsson, Karin
AU  - Jacobsson K
FAU - Strom, Katrin
AU  - Strom K
FAU - Lindberg, Martin
AU  - Lindberg M
FAU - Frykberg, Lars
AU  - Frykberg L
LA  - eng
SI  - GENBANK/AF130864
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Microbiology (Reading)
JT  - Microbiology (Reading, England)
JID - 9430468
RN  - 0 (Bacterial Proteins)
RN  - 0 (Carrier Proteins)
RN  - 0 (Glycoproteins)
RN  - 0 (Immunoglobulin G)
RN  - 0 (Membrane Proteins)
RN  - 0 (Peptide Library)
RN  - 0 (Sbi protein, Staphylococcus aureus)
RN  - 0 (beta 2-Glycoprotein I)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - *Bacterial Proteins
MH  - Bacteriophages/genetics
MH  - Binding Sites
MH  - Blotting, Western
MH  - Carrier Proteins/analysis/chemistry/genetics/*metabolism
MH  - Chromatography, Affinity
MH  - Glycoproteins/blood/chemistry/isolation & purification/*metabolism
MH  - Humans
MH  - Immunoglobulin G/*metabolism
MH  - Membrane Proteins/analysis/chemistry/*metabolism
MH  - Molecular Sequence Data
MH  - Peptide Library
MH  - Protein Binding
MH  - Staphylococcus aureus/chemistry/*metabolism
MH  - beta 2-Glycoprotein I
EDAT- 1999/04/17 00:00
MHDA- 1999/04/17 00:01
CRDT- 1999/04/17 00:00
PHST- 1999/04/17 00:00 [pubmed]
PHST- 1999/04/17 00:01 [medline]
PHST- 1999/04/17 00:00 [entrez]
AID - 10.1099/13500872-145-1-177 [doi]
PST - ppublish
SO  - Microbiology (Reading). 1999 Jan;145 ( Pt 1):177-183. doi: 
      10.1099/13500872-145-1-177.