PMID- 10209944
OWN - NLM
STAT- MEDLINE
DCOM- 19990429
LR  - 20190708
IS  - 0020-7136 (Print)
IS  - 0020-7136 (Linking)
VI  - 81
IP  - 3
DP  - 1999 May 5
TI  - Geographical clustering of human T-cell lymphotropic virus type I in Guadeloupe, 
      an endemic Caribbean area.
PG  - 330-4
AB  - Between January 1989 and December 1996, 59,426 blood donors from Guadeloupe 
      (French West Indies) were screened for antibodies to human T-cell lymphotropic 
      virus type I (HTLV-I). Of these, 195 were confirmed as being positive for HTLV-I, 
      yielding an overall prevalence of 0.33% [95% confidence interval (CI) 0.28-0.38]. 
      On multiple logistic regression analysis, risk factors for HTLV-I were female 
      gender [odds ratio (OR) 1.8; CI 1.3-2.4], increasing age (30-39 years, OR 2.2, CI 
      1.4-3.4; 40-49 years, OR 3.1, CI 2.1-4.7; > or =50 years, OR 5.6, CI 3.6-8.6) and 
      positive hepatitis B core antibodies (OR 2.0; CI 1.5-2.8). HTLV-I seropositivity 
      was also significantly associated with current residence in certain areas, 
      highlighting microgeographic clustering: individuals living along the Atlantic 
      Facade of Guadeloupe, which is a traditional sugar cane plantation area where 
      Africans were brought during slave trading, were at increased risk for HTLV-I 
      infection (OR 1.9; CI 1.3-2.7) compared with other areas in Guadeloupe devoted to 
      other activities. Our report of HTLV-I cluster identification in Guadeloupe 
      probably reflects both its low spread and its highly intrafamilial restricted 
      transmission within this endemic Caribbean population.
FAU - Rouet, F
AU  - Rouet F
AD  - Etablissement de Transfusion Sanguine, Hopital Ricou, Pointe-a-Pitre, Guadeloupe, 
      France.
FAU - Rabier, R
AU  - Rabier R
FAU - Foucher, C
AU  - Foucher C
FAU - Chancerel, B
AU  - Chancerel B
FAU - Agis, F
AU  - Agis F
FAU - Strobel, M
AU  - Strobel M
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Int J Cancer
JT  - International journal of cancer
JID - 0042124
RN  - 0 (Deltaretrovirus Antibodies)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age Factors
MH  - Aged
MH  - Cluster Analysis
MH  - Deltaretrovirus Antibodies/blood
MH  - Female
MH  - Guadeloupe/epidemiology
MH  - Human T-lymphotropic virus 1/*isolation & purification
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Seroepidemiologic Studies
EDAT- 1999/04/21 02:03
MHDA- 2000/06/20 09:00
CRDT- 1999/04/21 02:03
PHST- 1999/04/21 02:03 [pubmed]
PHST- 2000/06/20 09:00 [medline]
PHST- 1999/04/21 02:03 [entrez]
AID - 10.1002/(SICI)1097-0215(19990505)81:3<330::AID-IJC3>3.0.CO;2-2 [pii]
AID - 10.1002/(sici)1097-0215(19990505)81:3<330::aid-ijc3>3.0.co;2-2 [doi]
PST - ppublish
SO  - Int J Cancer. 1999 May 5;81(3):330-4. doi: 
      10.1002/(sici)1097-0215(19990505)81:3<330::aid-ijc3>3.0.co;2-2.