PMID- 10213960
OWN - NLM
STAT- MEDLINE
DCOM- 19990527
LR  - 20161124
IS  - 0018-2052 (Print)
IS  - 0018-2052 (Linking)
VI  - 48
IP  - 1
DP  - 1999 Mar
TI  - A case of aortitis syndrome and IgA nephropathy: possible role of human leukocyte 
      antigens in both diseases.
PG  - 25-9
AB  - A 51-year-old woman, who had both aortitis syndrome (Takayasu arteritis) and IgA 
      nephropathy, presented with hypertension, fever, a high erythrocyte sedimentation 
      rate, high C-reactive protein and serum IgG levels, proteinuria, and renal 
      dysfunction. Renal arteriography showed stenosis and poststenotic dilatation at 
      the origin of the right renal artery, as well as tortuosity of the left renal 
      artery branches and marked atrophy of the left kidney. Renal biopsy showed IgA 
      nephropathy with deposits of IgA, C3, and fibrinogen in the glomeruli and 
      arteriolosclerosis. The present patient had human leukocyte antigen (HLA)-B 52, 
      which is reported to be related to the aortitis syndrome, as well as HLA-DR 4, 
      which is possibly related to IgA nephropathy, suggesting that HLA status may be 
      involved in the pathogenesis of both diseases.
FAU - Kanahara, K
AU  - Kanahara K
AD  - Department of Internal Medicine, Onomichi General Hospital, Japan.
FAU - Yorioka, N
AU  - Yorioka N
FAU - Ogata, S
AU  - Ogata S
FAU - Ohira, N
AU  - Ohira N
FAU - Oobayashi, M
AU  - Oobayashi M
FAU - Kiso, T
AU  - Kiso T
FAU - Harada, Y
AU  - Harada Y
FAU - Komiya, H
AU  - Komiya H
FAU - Asakimori, Y
AU  - Asakimori Y
FAU - Taniguchi, Y
AU  - Taniguchi Y
FAU - Yamakido, M
AU  - Yamakido M
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Japan
TA  - Hiroshima J Med Sci
JT  - Hiroshima journal of medical sciences
JID - 0421060
RN  - 0 (HLA Antigens)
SB  - IM
MH  - Adult
MH  - Aortic Arch Syndromes/complications/diagnostic imaging/*immunology/pathology
MH  - Female
MH  - Glomerulonephritis, IGA/complications/diagnostic imaging/*immunology/pathology
MH  - HLA Antigens/*immunology
MH  - Humans
MH  - Radiography
EDAT- 1999/04/24 00:00
MHDA- 1999/04/24 00:01
CRDT- 1999/04/24 00:00
PHST- 1999/04/24 00:00 [pubmed]
PHST- 1999/04/24 00:01 [medline]
PHST- 1999/04/24 00:00 [entrez]
PST - ppublish
SO  - Hiroshima J Med Sci. 1999 Mar;48(1):25-9.