PMID- 10320012
OWN - NLM
STAT- MEDLINE
DCOM- 19990617
LR  - 20191210
IS  - 0304-3940 (Print)
IS  - 0304-3940 (Linking)
VI  - 264
IP  - 1-3
DP  - 1999 Apr 2
TI  - Effects of interstimulus interval on auditory event-related potentials in 
      congenitally blind and normally sighted humans.
PG  - 53-6
AB  - To test the hypothesis of auditory compensation after early visual deprivation, 
      congenitally blind and sighted adults performed an auditory discrimination task. 
      They had to detect a rare target tone among frequent standard tones. Stimuli were 
      presented with different interstimulus intervals (ISIs) (200, 1000, 2000 ms) and 
      the auditory-event related potentials to all tones and reaction times to targets 
      were recorded. Increasing ISIs resulted in an increasing amplitude of the vertex 
      response (N1-P2) in both groups, but this amplitude recovery was more pronounced 
      in the blind. Furthermore, targets elicited larger and more posteriorly 
      distributed N2 responses in the blind than in the sighted. Since target detection 
      times were shorter in the blind as well, these findings imply compensatory 
      adaptations within the auditory modality in humans blind from birth.
FAU - Roder, B
AU  - Roder B
AD  - Experimental and Biological Psychology, Philipps-University Marburg, Germany. 
      roeder@mailer.uni-marburg.edu
FAU - Rosler, F
AU  - Rosler F
FAU - Neville, H J
AU  - Neville HJ
LA  - eng
GR  - DC00128/DC/NIDCD NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Ireland
TA  - Neurosci Lett
JT  - Neuroscience letters
JID - 7600130
SB  - IM
MH  - Acoustic Stimulation/methods
MH  - Adaptation, Physiological/physiology
MH  - Adult
MH  - Blindness/*congenital/*physiopathology
MH  - Discrimination, Psychological/physiology
MH  - Evoked Potentials, Auditory/*physiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Neuronal Plasticity/physiology
MH  - Neuropsychological Tests
MH  - Reaction Time/physiology
MH  - Reference Values
EDAT- 1999/05/13 00:00
MHDA- 1999/05/13 00:01
CRDT- 1999/05/13 00:00
PHST- 1999/05/13 00:00 [pubmed]
PHST- 1999/05/13 00:01 [medline]
PHST- 1999/05/13 00:00 [entrez]
AID - S0304-3940(99)00182-2 [pii]
AID - 10.1016/s0304-3940(99)00182-2 [doi]
PST - ppublish
SO  - Neurosci Lett. 1999 Apr 2;264(1-3):53-6. doi: 10.1016/s0304-3940(99)00182-2.