PMID- 10329992
OWN - NLM
STAT- MEDLINE
DCOM- 19990607
LR  - 20190117
IS  - 0002-9513 (Print)
IS  - 0002-9513 (Linking)
VI  - 276
IP  - 5
DP  - 1999 May
TI  - Effect of protein intake and physical activity on 24-h pattern and rate of 
      macronutrient utilization.
PG  - E964-76
LID - 10.1152/ajpendo.1999.276.5.E964 [doi]
AB  - Effects of moderate physical activity (90 min at 45-50% of maximal O2 uptake 2 
      times daily) and "high" (2.5 g protein. kg-1. day-1, n = 6) or "normal" protein 
      intake (1.0 g protein. kg-1. day-1, n = 8) on the pattern and rate of 24-h 
      macronutrient utilization in healthy adult men were compared after a 
      diet-exercise-adjustment period of 6 days. Energy turnover (ET) was determined by 
      indirect and direct (suit) calorimetry, and "protein oxidation" was determined by 
      a 24-h continuous intravenous infusion of [1-13C]leucine. Subjects were in slight 
      positive energy balance during both studies. Protein contributed to a higher (22 
      vs. 10%) and carbohydrate (CHO) a lower (33 vs. 58%) proportion of total 24-h ET 
      on the high- vs. normal-protein intake. The highest contribution of fat to ET was 
      seen postexercise during fasting (73 and 61% of ET for high and normal, 
      respectively). With the high-protein diet the subjects were in a positive protein 
      (P < 0.001) and CHO balance (P < 0.05) and a negative fat balance (P < 0.05). The 
      increased ET postexercise was not explained by increased rates of urea production 
      and/or protein synthesis.
FAU - Forslund, A H
AU  - Forslund AH
AD  - Department of Medical Sciences and Nutrition, Uppsala University, SE-752 37 
      Uppsala, Sweden. Anders.Forslund@nutrition.uu.se
FAU - El-Khoury, A E
AU  - El-Khoury AE
FAU - Olsson, R M
AU  - Olsson RM
FAU - Sjodin, A M
AU  - Sjodin AM
FAU - Hambraeus, L
AU  - Hambraeus L
FAU - Young, V R
AU  - Young VR
LA  - eng
GR  - DK-15856/DK/NIDDK NIH HHS/United States
GR  - RR-88/RR/NCRR NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Am J Physiol
JT  - The American journal of physiology
JID - 0370511
RN  - 0 (Carbon Isotopes)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Proteins)
RN  - 0 (Proteins)
RN  - 8W8T17847W (Urea)
RN  - GMW67QNF9C (Leucine)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Calorimetry
MH  - Calorimetry, Indirect
MH  - Carbon Isotopes
MH  - Dietary Carbohydrates/administration & dosage/metabolism
MH  - Dietary Proteins/*administration & dosage/metabolism
MH  - *Energy Metabolism
MH  - Exercise/*physiology
MH  - Fasting
MH  - Humans
MH  - Leucine
MH  - Male
MH  - Oxidation-Reduction
MH  - Oxygen Consumption
MH  - Proteins/*metabolism
MH  - Urea/metabolism
EDAT- 1999/05/18 00:00
MHDA- 1999/05/18 00:01
CRDT- 1999/05/18 00:00
PHST- 1999/05/18 00:00 [pubmed]
PHST- 1999/05/18 00:01 [medline]
PHST- 1999/05/18 00:00 [entrez]
AID - 10.1152/ajpendo.1999.276.5.E964 [doi]
PST - ppublish
SO  - Am J Physiol. 1999 May;276(5):E964-76. doi: 10.1152/ajpendo.1999.276.5.E964.