PMID- 10354033 OWN - NLM STAT- MEDLINE DCOM- 20000504 LR - 20190704 IS - 0007-0963 (Print) IS - 0007-0963 (Linking) VI - 140 IP - 5 DP - 1999 May TI - Latex allergy in atopic children. PG - 919-21 AB - The incidence of positive circulating specific immunoglobulin E (IgE) antibodies to latex and evidence of clinical latex sensitivity appears to be increasing since its first description in 1979. Although heightened medical awareness may be a factor, exposure to latex products, particularly rubber gloves, has increased since the discovery of the human immunodeficiency virus (HIV). Atopic individuals are at greater risk of developing latex sensitivity. We identified seven children with atopic eczema who were known to have clinically significant latex allergy and examined the relationship of prior exposure to latex gloves. All children had significant serum levels of specific IgE to latex. Before developing clinical symptoms of latex allergy, all had been exposed to latex in the form of gloves during either inpatient or outpatient treatments of their skin. Exposure of atopic individuals to latex gloves could be a major risk factor for sensitization and could increase the incidence of serious reactions. FAU - Holme, S A AU - Holme SA AD - University Department of Dermatology, Western Infirmary, Dumbarton Road, Glasgow G11 6NB, U.K. FAU - Lever, R S AU - Lever RS LA - eng PT - Case Reports PT - Journal Article PL - England TA - Br J Dermatol JT - The British journal of dermatology JID - 0004041 RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - Child MH - Child, Preschool MH - Dermatitis, Atopic/*complications/immunology MH - Environmental Exposure MH - Female MH - Food Hypersensitivity/*complications/immunology MH - Gloves, Surgical MH - Humans MH - Immunoglobulin E/blood MH - Infant MH - Latex Hypersensitivity/*complications/immunology MH - Male EDAT- 1999/06/03 10:00 MHDA- 2000/05/08 09:00 CRDT- 1999/06/03 10:00 PHST- 1999/06/03 10:00 [pubmed] PHST- 2000/05/08 09:00 [medline] PHST- 1999/06/03 10:00 [entrez] AID - bjd2826 [pii] AID - 10.1046/j.1365-2133.1999.02826.x [doi] PST - ppublish SO - Br J Dermatol. 1999 May;140(5):919-21. doi: 10.1046/j.1365-2133.1999.02826.x.