PMID- 10366916
OWN - NLM
STAT- MEDLINE
DCOM- 19990629
LR  - 20190822
IS  - 0001-6470 (Print)
IS  - 0001-6470 (Linking)
VI  - 70
IP  - 2
DP  - 1999 Apr
TI  - Gene expressions of antiinflammatory mediators in THR retrieved interfacial 
      membranes.
PG  - 149-54
AB  - We investigated gene expression of antiinflammatory mediators in the interfacial 
      membranes retrieved at hip revision arthroplasty using reverse 
      transcription-polymerase chain reaction (RT-PCR). Levels of RT-PCR products were 
      compared with those of synovial tissue from patients with osteoarthrosis or 
      rheumatoid arthritis. Antiinflammatory mediators such as type II interleukin 
      (IL)-1 receptor, IL-4, IL-10, IL-1 receptor antagonist, and transforming growth 
      factor-beta 1 (TGF-beta 1) were expressed in the interfacial membrane. In 
      interfacial tissue, the level of IL-10 was lower, but that of the IL-1 receptor 
      antagonist higher than in diseased synovial tissue.
FAU - Nabae, M
AU  - Nabae M
AD  - Department of Orthopaedic Surgery, Shiga University of Medical Science, Japan.
FAU - Inoue, K
AU  - Inoue K
FAU - Ushiyama, T
AU  - Ushiyama T
FAU - Hukuda, S
AU  - Hukuda S
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Acta Orthop Scand
JT  - Acta orthopaedica Scandinavica
JID - 0370352
RN  - 0 (IL1RN protein, human)
RN  - 0 (Inflammation Mediators)
RN  - 0 (Interleukin 1 Receptor Antagonist Protein)
RN  - 0 (Receptors, Interleukin-1)
RN  - 0 (Sialoglycoproteins)
RN  - 0 (Transforming Growth Factor beta)
RN  - 130068-27-8 (Interleukin-10)
RN  - 207137-56-2 (Interleukin-4)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Arthritis, Rheumatoid/pathology
MH  - Case-Control Studies
MH  - Female
MH  - Gene Expression/*genetics/*immunology
MH  - Hip Prosthesis/*adverse effects
MH  - Humans
MH  - Inflammation
MH  - Inflammation Mediators/*analysis
MH  - Interleukin 1 Receptor Antagonist Protein
MH  - Interleukin-10/*analysis
MH  - Interleukin-4/*analysis
MH  - Male
MH  - Middle Aged
MH  - Osseointegration/*genetics/*immunology
MH  - Osteoarthritis/pathology
MH  - *Prosthesis Failure
MH  - Receptors, Interleukin-1/*analysis
MH  - Reoperation
MH  - Reverse Transcriptase Polymerase Chain Reaction
MH  - Sialoglycoproteins/*analysis
MH  - Synovial Membrane/*chemistry
MH  - Transforming Growth Factor beta/*analysis
EDAT- 1999/06/15 00:00
MHDA- 1999/06/15 00:01
CRDT- 1999/06/15 00:00
PHST- 1999/06/15 00:00 [pubmed]
PHST- 1999/06/15 00:01 [medline]
PHST- 1999/06/15 00:00 [entrez]
AID - 10.3109/17453679909011254 [doi]
PST - ppublish
SO  - Acta Orthop Scand. 1999 Apr;70(2):149-54. doi: 10.3109/17453679909011254.