PMID- 10376695
OWN - NLM
STAT- MEDLINE
DCOM- 19990716
LR  - 20190717
IS  - 0003-987X (Print)
IS  - 0003-987X (Linking)
VI  - 135
IP  - 6
DP  - 1999 Jun
TI  - Treatment of port-wine stains with a noncoherent pulsed light source: a 
      retrospective study.
PG  - 679-83
AB  - OBJECTIVE: We investigated whether a noncoherent intense pulsed light source 
      (IPLS) would be effective in therapy of port-wine stains (PWSs). DESIGN: To 
      evaluate the efficacy in treatment of PWSs with IPLS, a retrospective study was 
      initiated. SETTING: The data were collected by physicians working in private 
      practices and departments of university hospitals and medical centers, 
      respectively. PATIENTS: A total of 37 randomly selected patients with a total of 
      40 PWSs were included in the study. Clinical PWS characteristics recorded were 
      color and location of the PWS. INTERVENTIONS: All patients were treated with 
      IPLS. MAIN OUTCOME MEASURES: Data collected included treatment parameter 
      (filters, pulse duration, fluence, and pulse sequencing), percentage of 
      clearance, and side effects (purpura, blisters, crusting, altered pigmentation, 
      and scarring). RESULTS: Good and complete (70%-100%) clearance was achieved in 28 
      of 40 PWSs treated with IPLS. The average number of treatment sessions in PWSs 
      reaching 100% clearance included 4.0 for pink PWSs and 1.5 for red PWSs. The 
      average number of sessions for purple PWSs reaching good clearance (70%-99%) was 
      4.2 sessions. Parameters used most frequently were 515- and 550-nm cut-off 
      filters, pulse duration of 2.5 to 5.0 milliseconds, and fluences of 24 to 60 
      J/cm2. Side effects included purpura in 133 (76%), superficial blisters in 14 
      (8%), and crusting in 35 (20%). Transient pigmentation changes were seen in 10.8% 
      of patients (hypopigmentation in 3 [8.1%], hyperpigmentation in 1 [2.7%]). No 
      scarring was observed. CONCLUSION: Intense pulsed light source presents an 
      effective and safe method for treating PWSs, especially purple PWSs.
FAU - Raulin, C
AU  - Raulin C
AD  - Laserklinik, Karlsruhe, Germany. dres.raulin@t-online.de
FAU - Schroeter, C A
AU  - Schroeter CA
FAU - Weiss, R A
AU  - Weiss RA
FAU - Keiner, M
AU  - Keiner M
FAU - Werner, S
AU  - Werner S
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Arch Dermatol
JT  - Archives of dermatology
JID - 0372433
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Child
MH  - Child, Preschool
MH  - Female
MH  - Hamartoma/*therapy
MH  - Humans
MH  - Infant
MH  - Male
MH  - Middle Aged
MH  - Phototherapy/*methods
MH  - Retrospective Studies
MH  - Skin Diseases/*therapy
EDAT- 1999/06/22 00:00
MHDA- 1999/06/22 00:01
CRDT- 1999/06/22 00:00
PHST- 1999/06/22 00:00 [pubmed]
PHST- 1999/06/22 00:01 [medline]
PHST- 1999/06/22 00:00 [entrez]
AID - 10.1001/archderm.135.6.679 [doi]
PST - ppublish
SO  - Arch Dermatol. 1999 Jun;135(6):679-83. doi: 10.1001/archderm.135.6.679.