PMID- 10392273
OWN - NLM
STAT- MEDLINE
DCOM- 19990819
LR  - 20190831
IS  - 0160-564X (Print)
IS  - 0160-564X (Linking)
VI  - 23
IP  - 6
DP  - 1999 Jun
TI  - Cardiac autonomic nervous function during long-term nonpulsatile left heart 
      bypass.
PG  - 500-3
AB  - We investigated the changes in cardiac autonomic nervous activities during 
      long-term nonpulsatile left heart bypass (NLHB) by analyzing heart rate 
      variability. A pulsatile ventricular assist device was installed in 3 goats, and 
      pulsatile left heart bypass (PLHB) was conducted for 2 weeks. Then, NLHB was 
      maintained for the following 4 weeks. The segmental data of the R-R intervals 
      (R-Rs) was analyzed by maximum entropy spectral analysis. Changes in evaluated 
      parameters from the last week of PLHB to the 4th week of NLHB were as follows: 
      the mean R-Rs increased from 511 ms to 692 ms; the coefficient of variation of 
      R-R increased from 10.2 to 14.1%; the power of the low frequency band (LF) 
      increased from 747 ms2 to 2,855 ms2; the power of the high frequency band (HF) 
      increased from 512 ms2 to 1,270 ms2; and the ratio of LF to HF increased from 2.6 
      to 6.5. These results indicated that the cardiac autonomic nervous activity, both 
      sympathetic and parasympathetic, increased during long-term NLHB.
FAU - Nishinaka, T
AU  - Nishinaka T
AD  - Department of Artificial Organs, National Cardiovascular Center, Osaka, Japan. 
      nishinak@ri.ncvc.go.jp
FAU - Tatsumi, E
AU  - Tatsumi E
FAU - Nishimura, T
AU  - Nishimura T
FAU - Taenaka, Y
AU  - Taenaka Y
FAU - Masuzawa, T
AU  - Masuzawa T
FAU - Nakata, M
AU  - Nakata M
FAU - Takano, H
AU  - Takano H
FAU - Koyanagi, H
AU  - Koyanagi H
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Artif Organs
JT  - Artificial organs
JID - 7802778
SB  - IM
MH  - Analysis of Variance
MH  - Animals
MH  - Aorta/physiology
MH  - Autonomic Nervous System/*physiology
MH  - Blood Circulation/physiology
MH  - Blood Pressure/physiology
MH  - Goats
MH  - *Heart Bypass, Left
MH  - Heart Conduction System/*physiology
MH  - Heart Rate/physiology
MH  - Longitudinal Studies
MH  - Mammary Arteries/physiology
MH  - Parasympathetic Nervous System/physiology
MH  - Pulsatile Flow/physiology
MH  - Signal Processing, Computer-Assisted
MH  - Sympathetic Nervous System/physiology
MH  - Time Factors
EDAT- 1999/07/07 00:00
MHDA- 1999/07/07 00:01
CRDT- 1999/07/07 00:00
PHST- 1999/07/07 00:00 [pubmed]
PHST- 1999/07/07 00:01 [medline]
PHST- 1999/07/07 00:00 [entrez]
AID - 10.1046/j.1525-1594.1999.06390.x [doi]
PST - ppublish
SO  - Artif Organs. 1999 Jun;23(6):500-3. doi: 10.1046/j.1525-1594.1999.06390.x.