PMID- 10403010
OWN - NLM
STAT- MEDLINE
DCOM- 19990820
LR  - 20161021
IS  - 0125-877X (Print)
IS  - 0125-877X (Linking)
VI  - 17
IP  - 1
DP  - 1999 Mar
TI  - Effect of IVIG on the hair regrowth in a common variable immune deficiency 
      patient with alopecia universalis.
PG  - 59-62
AB  - Common variable immune deficiency (CVID) is associated with a variety of 
      autoimmune diseases. Alopecia universalis (AU), believed to have an autoimmune 
      basis, has been found in 1.6% of patients with CVID. Intravenous immunoglobulin 
      (IVIG) therapy is used in various immunodeficiency disorders including CVID, and 
      benefit has been shown in the therapy of autoimmune diseases. We report a patient 
      with CVID and AU treated with IVIG who experienced significant hair regrowth. An 
      8-year-old girl with CVID and AU was treated with IVIG 400 mg/kg every 4 weeks. 
      Since her second dose of IVIG, regrowth of eyelashes, eyebrows, body and scalp 
      hair was observed in this patient. At present, about 1 year treat-meant of IVIG, 
      significant hair regrowth is noted with 5-6 cm of scalp hair. We believe that 
      IVIG may be beneficial in the treatment of AU, at least in patients with CVID.
FAU - Boonyaleepun, S
AU  - Boonyaleepun S
AD  - Department of Pediatrics, University of Tennessee Medical Center, Knoxville, USA.
FAU - Boonyaleepun, C
AU  - Boonyaleepun C
FAU - Schlactus, J L
AU  - Schlactus JL
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Thailand
TA  - Asian Pac J Allergy Immunol
JT  - Asian Pacific journal of allergy and immunology
JID - 8402034
RN  - 0 (Immunoglobulins, Intravenous)
SB  - IM
MH  - Alopecia/complications/*therapy
MH  - Child
MH  - Common Variable Immunodeficiency/complications/*therapy
MH  - Female
MH  - Hair/*drug effects/growth & development
MH  - Humans
MH  - Immunoglobulins, Intravenous/*therapeutic use
MH  - Treatment Outcome
EDAT- 1999/07/14 00:00
MHDA- 1999/07/14 00:01
CRDT- 1999/07/14 00:00
PHST- 1999/07/14 00:00 [pubmed]
PHST- 1999/07/14 00:01 [medline]
PHST- 1999/07/14 00:00 [entrez]
PST - ppublish
SO  - Asian Pac J Allergy Immunol. 1999 Mar;17(1):59-62.