PMID- 10409525
OWN - NLM
STAT- MEDLINE
DCOM- 19990826
LR  - 20190503
IS  - 1355-6037 (Print)
IS  - 1468-201X (Electronic)
IS  - 1355-6037 (Linking)
VI  - 82
IP  - 2
DP  - 1999 Aug
TI  - Surgery for aortic stenosis in severely symptomatic patients older than 80 years: 
      experience in a single UK centre.
PG  - 138-42
AB  - OBJECTIVE: To ascertain the surgical risk and long term outcome of patients over 
      80 years old undergoing aortic valve replacement (AVR). DESIGN: Consecutive cases 
      with respective case note audit and a telephone questionnaire. SETTING: Single UK 
      cardiothoracic surgical centre. PATIENTS: 103 (48 male) patients over 80 years 
      old undergoing AVR. The median age was 82 years (80-95 years) and 95 of 103 
      patients were in New York Heart Association (NYHA) class III or IV. METHOD AND 
      RESULTS: Preoperative characteristics, operative course, cost, and outcome 
      measures were ascertained. Mean bypass time was 56 minutes and 25 patients had 
      simultaneous coronary artery bypass grafting. Overall mortality was 19 of 103. 
      Univariate analysis of pertinent variables found that impaired renal function and 
      peripheral vascular disease were significantly associated with early 
      postoperative death. 10 of 12 patients requiring ventilation for more than 24 
      hours died. The 50% actuarial survival was 62 months. Late complications were 
      uncommon with 92% of patients in NYHA class I or II at follow up. CONCLUSIONS: 
      AVR in patients over 80 years old has a significant risk. However, those patients 
      who survive experience significant benefit with good long term prospects for 
      general health and social independence.
FAU - Gilbert, T
AU  - Gilbert T
AD  - Department of Cardiology, John Radcliffe Hospital, Oxford OX3 9DU, UK.
FAU - Orr, W
AU  - Orr W
FAU - Banning, A P
AU  - Banning AP
LA  - eng
PT  - Comment
PT  - Journal Article
PL  - England
TA  - Heart
JT  - Heart (British Cardiac Society)
JID - 9602087
SB  - IM
CIN - Heart. 1999 Aug;82(2):119-20. PMID: 10409516
CIN - Heart. 1999 Aug;82(2):125. PMID: 10409520
CON - Heart. 1999 Aug;82(2):134-7. PMID: 10409524
CIN - Heart. 2000 May;83(5):583-4. PMID: 10836836
MH  - Aged
MH  - *Aged, 80 and over
MH  - *Aortic Valve
MH  - Aortic Valve Stenosis/complications/mortality/*surgery
MH  - Coronary Artery Bypass/economics/mortality
MH  - Costs and Cost Analysis
MH  - Female
MH  - *Heart Valve Prosthesis Implantation/economics/mortality
MH  - Humans
MH  - Kidney Diseases/complications/mortality
MH  - Male
MH  - Peripheral Vascular Diseases/complications/mortality
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Survival Rate
MH  - Treatment Outcome
PMC - PMC1729117
EDAT- 1999/07/20 00:00
MHDA- 1999/07/20 00:01
PMCR- 2002/08/01
CRDT- 1999/07/20 00:00
PHST- 1999/07/20 00:00 [pubmed]
PHST- 1999/07/20 00:01 [medline]
PHST- 1999/07/20 00:00 [entrez]
PHST- 2002/08/01 00:00 [pmc-release]
AID - 10.1136/hrt.82.2.138 [doi]
PST - ppublish
SO  - Heart. 1999 Aug;82(2):138-42. doi: 10.1136/hrt.82.2.138.