PMID- 10410319
OWN - NLM
STAT- MEDLINE
DCOM- 19990914
LR  - 20131121
IS  - 0018-1994 (Print)
IS  - 0018-1994 (Linking)
VI  - 45
IP  - 5
DP  - 1999 May
TI  - [A case of subclinical IgA nephropathy and cyclosporin associated arteriolopathy 
      diagnosed by non-episode biopsy of graft kidney after renal transplantation].
PG  - 349-53
AB  - We report a case of subclinical immunoglobulin A (IgA) nephropathy and 
      cyclosporin associated arteriolopathy following renal transplantation. A 
      39-year-old male with chronic glomerulonephritis received kidney transplantation 
      from a two- human leukocyte antigen (HLA) mismatched cadaveric donor. The initial 
      immunosuppressive therapy was triple-drug therapy with cyclosporin, prednisolone 
      and mizoribine. Four months after transplantation, he had an acute rejection 
      episode, and the renal function was recovered by steroid pulse and 
      15-deoxyspergualin therapy. Eight years after transplantation, we conducted a 
      non-episode biopsy of the renal allograft to examine subclinical lesions. The 
      histopathological findings showed cyclosporin associate arteriolopathy (CAA) and 
      IgA nephropathy. There was no sign of acute or chronic rejection. At the present 
      time, the renal function of the allograft is good. In conclusion, the non-episode 
      biopsy of renal allograft is useful for examination of subclinical lesions.
FAU - Namba, Y
AU  - Namba Y
AD  - Department of Urology, Osaka Seamen's Insurance Hospital.
FAU - Kyakuno, M
AU  - Kyakuno M
FAU - Nakamura, T
AU  - Nakamura T
FAU - Yamashiro, H
AU  - Yamashiro H
FAU - Okada, M
AU  - Okada M
FAU - Toki, K
AU  - Toki K
FAU - Ichimaru, N
AU  - Ichimaru N
FAU - Kokado, Y
AU  - Kokado Y
FAU - Takahara, S
AU  - Takahara S
FAU - Okuyama, A
AU  - Okuyama A
FAU - Oka, K
AU  - Oka K
FAU - Imai, E
AU  - Imai E
FAU - Kyo, M
AU  - Kyo M
LA  - jpn
PT  - Case Reports
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Hinyokika Kiyo
JT  - Hinyokika kiyo. Acta urologica Japonica
JID - 0421145
RN  - 0 (Immunosuppressive Agents)
RN  - 83HN0GTJ6D (Cyclosporine)
SB  - IM
MH  - Biopsy
MH  - Cyclosporine/*adverse effects
MH  - Glomerulonephritis, IGA/*diagnosis/pathology
MH  - Humans
MH  - Immunosuppressive Agents/*adverse effects
MH  - Kidney/*pathology
MH  - Kidney Transplantation/*pathology
MH  - Male
MH  - Middle Aged
MH  - *Renal Artery
MH  - Vascular Diseases/chemically induced/diagnosis/pathology
EDAT- 1999/07/20 00:00
MHDA- 1999/07/20 00:01
CRDT- 1999/07/20 00:00
PHST- 1999/07/20 00:00 [pubmed]
PHST- 1999/07/20 00:01 [medline]
PHST- 1999/07/20 00:00 [entrez]
PST - ppublish
SO  - Hinyokika Kiyo. 1999 May;45(5):349-53.