PMID- 10412863 OWN - NLM STAT- MEDLINE DCOM- 19990920 LR - 20131121 IS - 0931-041X (Print) IS - 0931-041X (Linking) VI - 13 IP - 5 DP - 1999 Jun TI - Hemodiafiltration for vancomycin overdose in a neonate with end-stage renal failure. PG - 423-5 AB - We describe continuous venovenous hemodiafiltration (CVVHD) with a high-flux membrane as a novel treatment modality for vancomycin overdose associated with renal insufficiency. CVVHD was used in a 6-day-old male with a solitary hypodysplastic kidney, suspected sepsis, and anuric renal failure who subsequently received an accidental tenfold overdose of vancomycin. We furthermore present evidence for the importance of countercurrent dialysis in addition to continuous hemofiltration for optimal vancomycin removal. FAU - Goebel, J AU - Goebel J AD - Department of Pediatrics, Tulane Medical School and Tulane Hospital for Children New Orleans, Louisiana, USA. FAU - Ananth, M AU - Ananth M FAU - Lewy, J E AU - Lewy JE LA - eng PT - Case Reports PT - Journal Article PL - Germany TA - Pediatr Nephrol JT - Pediatric nephrology (Berlin, Germany) JID - 8708728 RN - 6Q205EH1VU (Vancomycin) SB - IM MH - Drug Overdose MH - Hemodiafiltration/*methods MH - Humans MH - Infant, Newborn MH - Kidney/abnormalities MH - Kidney Failure, Chronic/chemically induced/*therapy MH - Male MH - Vancomycin/*poisoning EDAT- 1999/07/21 00:00 MHDA- 1999/07/21 00:01 CRDT- 1999/07/21 00:00 PHST- 1999/07/21 00:00 [pubmed] PHST- 1999/07/21 00:01 [medline] PHST- 1999/07/21 00:00 [entrez] AID - 10.1007/s004670050633 [doi] PST - ppublish SO - Pediatr Nephrol. 1999 Jun;13(5):423-5. doi: 10.1007/s004670050633.