PMID- 10429479
OWN - NLM
STAT- MEDLINE
DCOM- 19990913
LR  - 20180222
IS  - 0029-0831 (Print)
IS  - 0029-0831 (Linking)
VI  - 31
IP  - 4
DP  - 1999 Jul
TI  - [Frequent convulsions in the post-eruptive stage of exanthem subitum].
PG  - 310-6
AB  - We report here three infants with frequent convulsions in the post-eruptive stage 
      of exanthem subitum (ES) due to human herpesvirus 6 (HHV-6) infection. Postictal 
      electroencephalogram (EEG) showed in all the patients abnormal epileptic 
      discharges, which disappeared in the following by three to eighteen months. In 
      one case, brain magnetic resonance imaging (MRI) revealed focal gliosis. SPECT 
      demonstrated hypoperfusion of the lesion. In the cerebro spinal fluid (CSF) of 
      all the patients, HHV-6 DNA was negative on polymerase chain reaction (PCR) and 
      HHV-6 antibodies were not significantly increased. Although encephalitis has been 
      reported to complicate primary HHV-6 infection, our patients were not diagnosed 
      as having encephalitis because of the clinical, CSF, EEG and CT findings. 
      However, they had frequent convulsions. Not only virus invasion but also a 
      secondary reaction including vasculitis may cause the central nervous system 
      complications of HHV-6 infection. Frequent convulsions may occur in the 
      post-eruptic stage after HHV-6 infection.
FAU - Ojima, K
AU  - Ojima K
AD  - Department of Pediatrics, Koshigaya Hospital, Dokkyo University School of 
      Medicine, Saitama.
FAU - Sakuta, R
AU  - Sakuta R
FAU - Kagaya, A
AU  - Kagaya A
FAU - Saga, T
AU  - Saga T
FAU - Nagai, T
AU  - Nagai T
FAU - Soma, R
AU  - Soma R
LA  - jpn
PT  - Case Reports
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - No To Hattatsu
JT  - No to hattatsu = Brain and development
JID - 0215224
SB  - IM
MH  - Electroencephalography
MH  - Exanthema Subitum/*complications/physiopathology
MH  - Female
MH  - Humans
MH  - Infant
MH  - Male
MH  - Seizures/*etiology
EDAT- 1999/08/03 00:00
MHDA- 1999/08/03 00:01
CRDT- 1999/08/03 00:00
PHST- 1999/08/03 00:00 [pubmed]
PHST- 1999/08/03 00:01 [medline]
PHST- 1999/08/03 00:00 [entrez]
PST - ppublish
SO  - No To Hattatsu. 1999 Jul;31(4):310-6.