PMID- 10430521 OWN - NLM STAT- MEDLINE DCOM- 19990921 LR - 20191024 IS - 0967-2109 (Print) IS - 0967-2109 (Linking) VI - 7 IP - 4 DP - 1999 Jun TI - Multivalvular surgery for infective endocarditis. PG - 402-8 AB - The short and the long-term results of our experience with 25 consecutive patients who underwent multivalvular surgery for infective endocarditis are analysed. Preoperatively, 20/25 (80%) patients were in New York Heart Association (NYHA) stage III or IV, and 2/25 (8%) patients were in cardiogenic shock. All the diseased valves were replaced with mechanical bileaflet prosthesis except seven mitral valves and one tricuspid valve, which could be repaired. Major postoperative complications occurred in 3/25 (12%) patients: a fatal cerebral haemorrhage, a reversible cerebellar syndrome and an intractable heart failure, which required transplantation. During a mean follow-up of 4.7 years (range 6 months to 16.8 years), 7/25 (28%) patients suffered from valve-related complications: five bleedings (one died), one embolic event and one prosthetic valve thrombosis. The actuarial freedom of valve-related event at 10 years was 61.8 +/- 12.4%. There was no prosthetic endocarditis. At follow-up, 20/21 (95%) survivors were in NYHA stage I or II. Long-term outcome in our patient population operated on for multivalvular endocarditis, is satisfactory with no recurrent infection and excellent functional results. FAU - Mueller, X M AU - Mueller XM AD - Department of Cardiovascular Surgery, CHUV, Lausanne, Switzerland. xavier.mueller@chuv.hospvd.ch FAU - Tevaearai, H T AU - Tevaearai HT FAU - Stumpe, F AU - Stumpe F FAU - Fischer, A P AU - Fischer AP FAU - Hurni, M AU - Hurni M FAU - Ruchat, P AU - Ruchat P FAU - von Segesser, L K AU - von Segesser LK LA - eng PT - Clinical Trial PT - Journal Article PL - England TA - Cardiovasc Surg JT - Cardiovascular surgery (London, England) JID - 9308765 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Aortic Valve/*surgery MH - *Bioprosthesis MH - Disease-Free Survival MH - Endocarditis, Bacterial/complications/mortality/*surgery MH - Female MH - Follow-Up Studies MH - Heart Valve Diseases/etiology/mortality/surgery MH - Heart Valve Prosthesis Implantation/*methods/mortality MH - Humans MH - Male MH - Middle Aged MH - Mitral Valve/*surgery MH - Postoperative Complications MH - Severity of Illness Index MH - Survival Rate MH - Thromboembolism/etiology MH - Time Factors MH - Tricuspid Valve/*surgery EDAT- 1999/08/03 00:00 MHDA- 1999/08/03 00:01 CRDT- 1999/08/03 00:00 PHST- 1999/08/03 00:00 [pubmed] PHST- 1999/08/03 00:01 [medline] PHST- 1999/08/03 00:00 [entrez] AID - S0967-2109(98)00152-5 [pii] AID - 10.1016/s0967-2109(98)00152-5 [doi] PST - ppublish SO - Cardiovasc Surg. 1999 Jun;7(4):402-8. doi: 10.1016/s0967-2109(98)00152-5.