PMID- 10440648 OWN - NLM STAT- MEDLINE DCOM- 19990916 LR - 20190921 IS - 0886-0440 (Print) IS - 0886-0440 (Linking) VI - 13 IP - 5 DP - 1998 Sep-Oct TI - Partial left ventriculectomy in patients with dialated failing ventricle. PG - 335-42 AB - BACKGROUND: While partial left ventriculectomy (PLV) improves left ventricular energetic efficiency, concomitant reduction in mitral regurgitation may improve ventricular function. METHODS: Two hundred ninety-five patients undergoing lateral ventricular wall excision between the papillary muscles (lateral PLV) and 101 patients with an additional excision of papillary muscles and mitral valve replacement (extended PLV) were compared with 65 patients undergoing excision of anterior wall or ventricular aneurysm (anterior PLV). RESULTS: All patients had reduced functional capacity, New York Heart Association (NYHA) Class III to IV (3.62+/-0.49). Etiologies were cardiomyopathy (37.3%), coronary artery disease (32.3%), valvular disease (19.7%), Chagas' disease (7.8%), and others (2.8%). Patients undergoing lateral and extended PLV had cardiomyopathy as the primary cause of heart failure, while a majority of anterior PLV patients had ischemic disease. Associated procedures included mitral valvuloplasty or replacement (lateral PLV 67%, extended PLV 100%, anterior PLV 40%) and tricuspid annuloplasty (67%, 76%, 28%, respectively.) In each group after surgery, end-systolic dimension decreased more than end-diastolic dimension despite reduced mitral regurgitation. Although extended PLV resulted in greater volume reduction and less mitral regurgitation, these patients had delayed recovery and poor survival. Patients with valvular disease had the most advanced myocardial hypertrophy with the best survival, while those with Chagas' disease had more severe myocarditis, interstitial fibrosis, and the poorest survival. CONCLUSION: Lateral PLV improved hemodynamics and functional capacity as much as aneurysmectomy by reducing ventricular volume and mitral regurgitation. Inclusion and exclusion criteria have to be sought to make PLV safer and more effective. FAU - Kawaguchi, A T AU - Kawaguchi AT AD - Cardiovascular Surgery and Transplantation, Tokai University School of Medicine, Isehara, Japan. akira@is.icc.u-tokai.ac.jp FAU - Bergsland, J AU - Bergsland J FAU - Ishibashi-Ueda, H AU - Ishibashi-Ueda H FAU - Ujiie, T AU - Ujiie T FAU - Shimura, S AU - Shimura S FAU - Koide, S AU - Koide S FAU - Salerno, T A AU - Salerno TA FAU - Batista, R J AU - Batista RJ LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - J Card Surg JT - Journal of cardiac surgery JID - 8908809 SB - IM MH - Cardiac Surgical Procedures/*methods MH - Echocardiography, Doppler MH - Female MH - Follow-Up Studies MH - Heart Failure/etiology/mortality/*surgery MH - Heart Ventricles/diagnostic imaging/physiopathology/*surgery MH - Humans MH - Male MH - Middle Aged MH - Myocardial Contraction MH - Retrospective Studies MH - Survival Rate MH - Treatment Outcome MH - Ventricular Dysfunction/complications/mortality/*surgery EDAT- 1999/08/10 00:00 MHDA- 1999/08/10 00:01 CRDT- 1999/08/10 00:00 PHST- 1999/08/10 00:00 [pubmed] PHST- 1999/08/10 00:01 [medline] PHST- 1999/08/10 00:00 [entrez] AID - 10.1111/j.1540-8191.1998.tb01094.x [doi] PST - ppublish SO - J Card Surg. 1998 Sep-Oct;13(5):335-42. doi: 10.1111/j.1540-8191.1998.tb01094.x.