PMID- 10448137
OWN - NLM
STAT- MEDLINE
DCOM- 19990902
LR  - 20191210
IS  - 0952-7915 (Print)
IS  - 0952-7915 (Linking)
VI  - 11
IP  - 4
DP  - 1999 Aug
TI  - The role of dendritic cells in the induction and regulation of immunity to 
      microbial infection.
PG  - 392-9
AB  - Dendritic cells (DCs) play a critical role in the initiation and regulation of 
      immune responses. Recent advances have begun to uncover the nature and diversity 
      of DC-pathogen interactions and the modulation of DC function by microbial 
      stimuli. Antigen pulsed DCs have also been shown in several infection models to 
      induce high levels of protective immunity and to display immunotherapeutic 
      potential. The study of the function of DCs in the response to infection is thus 
      an exciting and rapidly expanding field with important implications for both 
      fundamental and clinical immunology.
FAU - Reis e Sousa, C
AU  - Reis e Sousa C
AD  - Immunobiology Laboratory, Imperial Cancer Research Fund, 44 Lincoln's Inn Fields, 
      Holborn, London, WC2A 3PX, UK. caetano@icrf.icnet.uk
FAU - Sher, A
AU  - Sher A
FAU - Kaye, P
AU  - Kaye P
LA  - eng
PT  - Journal Article
PT  - Review
PL  - England
TA  - Curr Opin Immunol
JT  - Current opinion in immunology
JID - 8900118
SB  - IM
MH  - Animals
MH  - Antigen Presentation
MH  - Dendritic Cells/*physiology
MH  - Humans
MH  - Infections/*immunology
MH  - Protozoan Infections/immunology
MH  - T-Lymphocytes/physiology
MH  - Vaccination
RF  - 76
EDAT- 1999/08/17 00:00
MHDA- 1999/08/17 00:01
CRDT- 1999/08/17 00:00
PHST- 1999/08/17 00:00 [pubmed]
PHST- 1999/08/17 00:01 [medline]
PHST- 1999/08/17 00:00 [entrez]
AID - S0952-7915(99)80066-1 [pii]
AID - 10.1016/S0952-7915(99)80066-1 [doi]
PST - ppublish
SO  - Curr Opin Immunol. 1999 Aug;11(4):392-9. doi: 10.1016/S0952-7915(99)80066-1.