PMID- 10456400 OWN - NLM STAT- MEDLINE DCOM- 19990930 LR - 20190513 IS - 1010-7940 (Print) IS - 1010-7940 (Linking) VI - 16 IP - 1 DP - 1999 Jul TI - Angioscopic video-assisted pulmonary endarterectomy for post-embolic pulmonary hypertension. PG - 38-43 AB - OBJECTIVES: To assess whether the use of video-assisted angioscopy would increase the outcome of pulmonary thromboendarterectomy (PTE). METHODS: PTE included a median sternotomy, intrapericardial dissection of the superior vena cava, institution of cardiopulmonary bypass, deep hypothermia and sequential circulatory arrest periods. It was always performed through two separate arteriotomies on both main intrapericardial pulmonary arteries, into which a rigid 5 mm angioscope connected to a video camera was introduced to increase the visibility and endarterectomies. RESULTS: From January 1996 to July 1998, 68 consecutive patients (35 males and 33 females) aged 54.3 +/- 13.5 years underwent PTE. Patients were in New York Heart Association (NYHA) class II (n = 2), III (n = 43) or IV (n = 23) with the following hemodynamics: mean pulmonary arterial pressure (PAP) 54 +/- 13 mmHg; cardiac output (CO): 3.8 +/- 0.8 l/min, and total pulmonary resistance (TPR): 1207 +/- 416 dyne x s x cm(-5). The cumulated circulatory arrest time was 23 +/- 12 min and postoperative length of ventilatory support 10 +/- 12 days. Nine patients died, for an overall in-hospital mortality of 13.2%. The functional outcome in surviving patients was significantly improved (P < 0.0001) both clinically (NYHA class 3.2 +/- 0.5 vs. 1.3 +/- 0.6) and hemodynamically (PAP (mmHg) 53.1 +/- 13 vs. 30.2 +/- 11.8, CI (l/min per m2) 2.1 +/- 0.5 vs. 2.8 +/- 0.6, TPR (dyne x s x cm(-5)) 1174 +/- 416 vs. 519 +/- 250). CONCLUSIONS: Video-assisted angioscopy improves the quality and degree of pulmonary endarterectomy expanding the indications to include patients with previously inaccessible distal disease. FAU - Dartevelle, P AU - Dartevelle P AD - Service of Thoracic and Vascular Surgery and Heart-Lung Transplantation, Marie Lannelongue Hospital, Paris-Sud University, Le Plessis Robinson, France. phdart@pratique.fr FAU - Fadel, E AU - Fadel E FAU - Chapelier, A AU - Chapelier A FAU - Macchiarini, P AU - Macchiarini P FAU - Cerrina, J AU - Cerrina J FAU - Parquin, F AU - Parquin F FAU - Simonneau, F AU - Simonneau F FAU - Simonneau, G AU - Simonneau G LA - eng PT - Journal Article PL - Germany TA - Eur J Cardiothorac Surg JT - European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery JID - 8804069 SB - IM MH - Adult MH - Aged MH - *Angioscopy MH - Chronic Disease MH - *Endarterectomy MH - Female MH - Humans MH - Hypertension, Pulmonary/etiology/physiopathology/*surgery MH - Male MH - Middle Aged MH - Pulmonary Artery/*surgery MH - Pulmonary Embolism/complications MH - Treatment Outcome MH - Video Recording EDAT- 1999/08/24 00:00 MHDA- 1999/08/24 00:01 CRDT- 1999/08/24 00:00 PHST- 1999/08/24 00:00 [pubmed] PHST- 1999/08/24 00:01 [medline] PHST- 1999/08/24 00:00 [entrez] AID - S1010794099001165 [pii] AID - 10.1016/s1010-7940(99)00116-5 [doi] PST - ppublish SO - Eur J Cardiothorac Surg. 1999 Jul;16(1):38-43. doi: 10.1016/s1010-7940(99)00116-5.