PMID- 10496071
OWN - NLM
STAT- MEDLINE
DCOM- 19991020
LR  - 20231213
IS  - 1434-5161 (Print)
IS  - 1434-5161 (Linking)
VI  - 44
IP  - 5
DP  - 1999
TI  - Molecular cloning, expression, and mapping of a novel human cDNA, GRP17, highly 
      homologous to human gadd45 and murine MyD118.
PG  - 300-3
AB  - From a human placenta cDNA library, we isolated a novel gene whose predicted 
      product is highly homologous in amino acid sequence to human gadd45 and murine 
      MyD118 proteins (about 55% and 52% identity, respectively). The cDNA clone, 
      designated GRP17 (gadd-related protein, 17 kDa), contained a 477-bp open reading 
      frame encoding 159 amino acids. Northern blot analysis revealed strong expression 
      of a 1.35-kb transcript in heart, placenta, liver, skeletal muscle, prostate, 
      testis, and ovary. A 1.7-kb additional transcript was detected in liver. We 
      assigned the GRP17 gene to chromosome 9q22.1-q22.2 by fluorescence in situ 
      hybridization (FISH).
FAU - Suzuki, M
AU  - Suzuki M
AD  - Otsuka GEN Research Institute, Otsuka Pharmaceutical Co. Ltd., Tokushima, Japan.
FAU - Watanabe, T K
AU  - Watanabe TK
FAU - Fujiwara, T
AU  - Fujiwara T
FAU - Nakamura Yp6
AU  - Nakamura Yp6
FAU - Takahashi, E
AU  - Takahashi E
FAU - Tanigami, A
AU  - Tanigami A
LA  - eng
SI  - GENBANK/D83023
PT  - Journal Article
PL  - England
TA  - J Hum Genet
JT  - Journal of human genetics
JID - 9808008
RN  - 0 (Antigens, Differentiation)
RN  - 0 (Carrier Proteins)
RN  - 0 (DNA, Complementary)
RN  - 0 (GADD45B protein, human)
RN  - 0 (GADD45G protein, human)
RN  - 0 (Gadd45b protein, mouse)
RN  - 0 (Intracellular Signaling Peptides and Proteins)
RN  - 0 (Proteins)
RN  - 0 (Recombinant Proteins)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Antigens, Differentiation/biosynthesis/chemistry/*genetics
MH  - Base Sequence
MH  - *Carrier Proteins
MH  - Chromosome Mapping
MH  - *Chromosomes, Human, Pair 9
MH  - Cloning, Molecular
MH  - DNA Damage
MH  - DNA, Complementary/genetics
MH  - Female
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - *Intracellular Signaling Peptides and Proteins
MH  - Male
MH  - Mice
MH  - Molecular Sequence Data
MH  - Organ Specificity
MH  - Pregnancy
MH  - Proteins/chemistry/*genetics
MH  - Recombinant Proteins/biosynthesis/chemistry
MH  - Sequence Alignment
MH  - Sequence Homology, Amino Acid
MH  - Transcription, Genetic
MH  - GADD45 Proteins
EDAT- 1999/09/25 00:00
MHDA- 1999/09/25 00:01
CRDT- 1999/09/25 00:00
PHST- 1999/09/25 00:00 [pubmed]
PHST- 1999/09/25 00:01 [medline]
PHST- 1999/09/25 00:00 [entrez]
AID - 10.1007/s100380050164 [doi]
PST - ppublish
SO  - J Hum Genet. 1999;44(5):300-3. doi: 10.1007/s100380050164.