PMID- 10504086
OWN - NLM
STAT- MEDLINE
DCOM- 19991109
LR  - 20220210
IS  - 1081-597X (Print)
IS  - 1081-597X (Linking)
VI  - 15
IP  - 5
DP  - 1999 Sep-Oct
TI  - New fixation device for photorefractive surgery and its effect on corneal 
      epithelial wound healing.
PG  - 594-601
AB  - PURPOSE: A new eyeball fixation device during photorefractive surgery was 
      designed and tested. The device fixates the eyeball by means of a suction ring, 
      and is then fixated to the headrest of the patient's chair via clipper and metal 
      frames. METHODS: Photorefractive keratectomy (PRK) was performed on PMMA contact 
      lenses placed over the patient's cornea (n=6) to evaluate smoothness of the 
      ablated surface and on rabbit (n=24) and patient (n=30) corneas for evaluation of 
      wound healing time. Decentration with fixation was examined using 
      videokeratography after PRK. RESULTS: After fixation, only small amounts of 
      corneal movement from the patient's pulsating heart were noted. The mean 
      smoothness (root mean square) of the PMMA contact lens ablated surface was 0.43 
      +/- 0.16 microm in non-fixated eyes and 0.26 +/-0.05 microm in fixated eyes. Mean 
      epithelial healing rate was 47.93 +/- 21.80 microm/hr in non-fixated rabbit eyes 
      and 66.49 +/- 20 microm/hr in fixated rabbit eyes. Mean epithelial healing time 
      was 3.47 +/- 1.11 days in non-fixated human eyes and 2.53 +/- 0.51 days in 
      fixated human eyes. Mean decentration after PRK was 0.30 +/- 0.28 mm in fixated 
      human eyes. CONCLUSION: Fixating the eyeball allows less movement of the eye and 
      achieves a smoother ablation surface for more rapid epithelial healing after PRK.
FAU - Kim, E K
AU  - Kim EK
AD  - Department of Ophthalmology, Yonsei Institute of Vision Research, Yonsei 
      University College of Medicine, Seoul, Korea.
FAU - Lee, D H
AU  - Lee DH
FAU - Park, J W
AU  - Park JW
FAU - Chu, Y K
AU  - Chu YK
FAU - Seo, K Y
AU  - Seo KY
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - J Refract Surg
JT  - Journal of refractive surgery (Thorofare, N.J. : 1995)
JID - 9505927
SB  - IM
MH  - Adult
MH  - Animals
MH  - Corneal Topography
MH  - Epithelium, Corneal/*pathology/surgery
MH  - Equipment Design
MH  - Eye Movements
MH  - Female
MH  - Humans
MH  - Lasers, Excimer
MH  - Male
MH  - Middle Aged
MH  - Myopia/*pathology/surgery
MH  - Photorefractive Keratectomy/*instrumentation
MH  - Rabbits
MH  - Retrospective Studies
MH  - Treatment Outcome
MH  - *Wound Healing
EDAT- 1999/09/30 00:00
MHDA- 1999/09/30 00:01
CRDT- 1999/09/30 00:00
PHST- 1999/09/30 00:00 [pubmed]
PHST- 1999/09/30 00:01 [medline]
PHST- 1999/09/30 00:00 [entrez]
AID - 10.3928/1081-597X-19990901-14 [doi]
PST - ppublish
SO  - J Refract Surg. 1999 Sep-Oct;15(5):594-601. doi: 10.3928/1081-597X-19990901-14.