PMID- 10504199
OWN - NLM
STAT- MEDLINE
DCOM- 19991110
LR  - 20061115
IS  - 0022-3034 (Print)
IS  - 0022-3034 (Linking)
VI  - 41
IP  - 1
DP  - 1999 Oct
TI  - From visual experience to visual function: roles of neurotrophins.
PG  - 119-26
AB  - Recently, a role for neurotrophins in regulating cortical developmental 
      plasticity has clearly emerged. We present in this review a summary of the early 
      data on the action of nerve growth factor (NGF) in visual cortical development 
      and plasticity in the rat and of other neurotrophins in the visual cortex of 
      other mammals. In addition, to clarify the differences in the results obtained 
      with the various neurotrophins in different animal preparations, we also report 
      new data on the action of NGF, brain-derived neurotrophic factor (BDNF), 
      neurotrophin (NT)3, and NT4 in the same preparation-namely, the visual cortex of 
      the rat. We discuss old and new results in a physiological model in which 
      different neurotrophins play different roles in regulating visual cortical 
      development and plasticity by acting on different neural targets, such as lateral 
      geniculate nucleus (LGN) afferents, intracortical circuitry, and subcortical 
      afferents, and propose a tentative scheme summarizing these actions.
CI  - Copyright 1999 John Wiley & Sons, Inc.
FAU - Berardi, N
AU  - Berardi N
AD  - Istituto di Neurofisiologia del CNR e Scuola Normale Superiore, Via S. Zeno 51, 
      56127 Pisa, Italy.
FAU - Maffei, L
AU  - Maffei L
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - United States
TA  - J Neurobiol
JT  - Journal of neurobiology
JID - 0213640
RN  - 0 (Nerve Growth Factors)
RN  - 0 (Neurotransmitter Agents)
SB  - IM
MH  - Animals
MH  - Nerve Growth Factors/*physiology
MH  - Neurotransmitter Agents/*physiology
MH  - *Visual Cortex/chemistry/growth & development/physiology
RF  - 48
EDAT- 1999/09/30 00:00
MHDA- 1999/09/30 00:01
CRDT- 1999/09/30 00:00
PHST- 1999/09/30 00:00 [pubmed]
PHST- 1999/09/30 00:01 [medline]
PHST- 1999/09/30 00:00 [entrez]
AID - 10.1002/(SICI)1097-4695(199910)41:1<119::AID-NEU15>3.0.CO;2-N [pii]
PST - ppublish
SO  - J Neurobiol. 1999 Oct;41(1):119-26.