PMID- 10527480 OWN - NLM STAT- MEDLINE DCOM- 19991209 LR - 20190910 IS - 8755-1039 (Print) IS - 1097-0339 (Linking) VI - 21 IP - 5 DP - 1999 Nov TI - Diagnostic intraocular fine-needle aspiration biopsy--An experience in three cases of retinoblastoma. PG - 331-4 AB - Ophthalmoscopically guided intraocular fine-needle aspiration biopsy (FNAB) under general anesthesia was performed in three suspected cases of retinoblastoma (Rb). The first case presented with uveitis and the second with unusual radiological features. The third case had classical clinical features of bilateral Rb but the parents refused enucleation. After a cytologic diagnosis of retinoblastoma, two cases were subjected to enucleation and a histologic confirmation was obtained. The present article discusses the technique of guided intraocular FNAB and its limitations as well as utility in the preoperative diagnosis of retinoblastoma (Rb). The authors are of the opinion that FNAB should be considered a viable diagnostic option in selected cases of leucocoria when conventional investigative modalities prove inconclusive or for tissue diagnosis when a patient of suspected Rb refuses enucleation. CI - Copyright 1999 Wiley-Liss, Inc. FAU - Sen, S AU - Sen S AD - Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India. SSen@Medinsternet.in FAU - Singha, U AU - Singha U FAU - Kumar, H AU - Kumar H FAU - Ghose, S AU - Ghose S FAU - Sarkar, T AU - Sarkar T FAU - Bajaj, M S AU - Bajaj MS LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Diagn Cytopathol JT - Diagnostic cytopathology JID - 8506895 SB - IM MH - *Biopsy, Needle/methods MH - Child MH - Child, Preschool MH - Female MH - Humans MH - Male MH - Retinal Neoplasms/diagnostic imaging/*pathology MH - Retinoblastoma/diagnostic imaging/*pathology MH - Ultrasonography EDAT- 1999/10/20 00:00 MHDA- 1999/10/20 00:01 CRDT- 1999/10/20 00:00 PHST- 1999/10/20 00:00 [pubmed] PHST- 1999/10/20 00:01 [medline] PHST- 1999/10/20 00:00 [entrez] AID - 10.1002/(SICI)1097-0339(199911)21:5<331::AID-DC7>3.0.CO;2-K [pii] AID - 10.1002/(sici)1097-0339(199911)21:5<331::aid-dc7>3.0.co;2-k [doi] PST - ppublish SO - Diagn Cytopathol. 1999 Nov;21(5):331-4. doi: 10.1002/(sici)1097-0339(199911)21:5<331::aid-dc7>3.0.co;2-k.