PMID- 10534680 OWN - NLM STAT- MEDLINE DCOM- 19991118 LR - 20190709 IS - 0190-9622 (Print) IS - 0190-9622 (Linking) VI - 41 IP - 5 Pt 2 DP - 1999 Nov TI - Adult-onset angiofibroma and multiple endocrine neoplasia type I. PG - 890-2 AB - Multiple endocrine neoplasia type 1 (MEN 1) predisposes affected persons to neoplasms of the parathyroid glands, the endocrine pancreas, the anterior pituitary, and the duodenum. We report the first case of adult-onset multiple angiofibromas of the central face associated with MEN 1. Seven siblings also developed adult-onset angiofibromas, none with evidence of tuberous sclerosis. Basic fibroblast growth factor (BFGF) is elevated in many patients with MEN 1 and may play a pathogenetic role. FAU - Hoang-Xuan, T AU - Hoang-Xuan T AD - Departments of Dermatology and Clinical Research, Naval Medical Center, San Diego, California 92134-1005, USA. Hoangxuan@pol.net FAU - Steger, J W AU - Steger JW LA - eng PT - Case Reports PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - J Am Acad Dermatol JT - Journal of the American Academy of Dermatology JID - 7907132 SB - IM MH - Adenoma/complications/pathology MH - Adult MH - Angiofibroma/*complications/pathology MH - Face MH - Humans MH - Male MH - Multiple Endocrine Neoplasia Type 1/*complications MH - Paraneoplastic Syndromes/pathology MH - Pituitary Neoplasms/complications MH - Skin Neoplasms/*complications/pathology EDAT- 1999/10/27 00:00 MHDA- 1999/10/27 00:01 CRDT- 1999/10/27 00:00 PHST- 1999/10/27 00:00 [pubmed] PHST- 1999/10/27 00:01 [medline] PHST- 1999/10/27 00:00 [entrez] AID - S0190-9622(99)70353-1 [pii] AID - 10.1016/s0190-9622(99)70353-1 [doi] PST - ppublish SO - J Am Acad Dermatol. 1999 Nov;41(5 Pt 2):890-2. doi: 10.1016/s0190-9622(99)70353-1.