PMID- 10540836
OWN - NLM
STAT- MEDLINE
DCOM- 20000105
LR  - 20131121
IS  - 1343-3490 (Print)
IS  - 1343-3490 (Linking)
VI  - 37
IP  - 9
DP  - 1999 Sep
TI  - [A case of common variable immunodeficiency that responded to long-term 
      erythromycin chemotherapy].
PG  - 699-703
AB  - A 32-year-old woman with common variable immunodeficiency (CVID) accompanied by 
      sinopulmonary infection was evaluated for purulent sputum, cough, and nasal 
      obstruction that did not respond to regular intravenous immunoglobin (IVIG) 
      infusion. Chest X-ray films revealed bronchiectasis affecting both lung bases, 
      and a bacteriological examination of sputum was positive for Pseudomonas 
      aeruginosa. Long-term chemotherapy with erythromycin (EM) was started, and the 
      patient's respiratory symptoms gradually subsided. Sinopulmonary infection is the 
      dominant clinical complication in patients with CVID. This case suggested that 
      long-term EM chemotherapy is useful for the treatment of IVIG-refractory 
      sinopulmonary infection associated with CVID.
FAU - Maeda, K
AU  - Maeda K
AD  - Department of Internal Medicine II, Nara Medical University, Japan.
FAU - Teranishi, T
AU  - Teranishi T
FAU - Majima, T
AU  - Majima T
FAU - Ueda, K
AU  - Ueda K
FAU - Yoshimoto, E
AU  - Yoshimoto E
FAU - Sakamoto, M
AU  - Sakamoto M
FAU - Konishi, M
AU  - Konishi M
FAU - Hamada, K
AU  - Hamada K
FAU - Mikasa, K
AU  - Mikasa K
FAU - Narita, N
AU  - Narita N
LA  - jpn
PT  - Case Reports
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Nihon Kokyuki Gakkai Zasshi
JT  - Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society
JID - 9808802
RN  - 0 (Anti-Bacterial Agents)
RN  - 63937KV33D (Erythromycin)
SB  - IM
MH  - Adult
MH  - Anti-Bacterial Agents/*administration & dosage
MH  - Common Variable Immunodeficiency/*drug therapy
MH  - Drug Administration Schedule
MH  - Erythromycin/*administration & dosage
MH  - Female
MH  - Humans
EDAT- 1999/12/14 00:00
MHDA- 1999/12/14 00:01
CRDT- 1999/12/14 00:00
PHST- 1999/12/14 00:00 [pubmed]
PHST- 1999/12/14 00:01 [medline]
PHST- 1999/12/14 00:00 [entrez]
PST - ppublish
SO  - Nihon Kokyuki Gakkai Zasshi. 1999 Sep;37(9):699-703.