PMID- 10558409
OWN - NLM
STAT- MEDLINE
DCOM- 19991109
LR  - 20220311
IS  - 0097-6326 (Print)
IS  - 0097-6326 (Linking)
VI  - 64
IP  - 55
DP  - 1999 Mar 23
TI  - National Institute of Environmental Health Sciences (NIEHS); the Murine Local 
      Lymph Node Assay: a Test Method for Assessing the Allergic Contact Dermatitis 
      Potential of Chemicals/Compounds, report now available. Public Health Service.
PG  - 14006-7
AB  - The report entitled "The Murine Local Lymph Node Assay: A Test Method for 
      Assessing the Allergic Contact Dermatitis Potential of Chemicals/Compounds," NIH 
      Publication 99-4494, is now available and may be obtained as described in this 
      notice. The report describes the results of an independent peer review evaluation 
      of the validation status of the Local Lymph Node Assay (LLNA) that was conducted 
      on September 17, 1998 (Federal Register 63 FR 37405-6, July 10, 1998). The (LLNA) 
      was proposed as an alternative toxicological test method for assessing the 
      allergic contact dermatitis (contact hypersensitivity) potential of chemicals and 
      products. The review was coordinated by the Interagency Coordinating Committee on 
      the Validation of Alternative Methods (ICCVAM) and the National Toxicology 
      Program (NTP) Interagency Center for the Evaluation of Alternative Toxicological 
      Methods (NICEATM). The review was sponsored by the National Institute of 
      Environmental Health Sciences and the NTP.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Fed Regist
JT  - Federal register
JID - 7808722
MH  - Animal Testing Alternatives/legislation & jurisprudence
MH  - Animals
MH  - Dermatitis, Allergic Contact/*etiology
MH  - *Guidelines as Topic
MH  - Guinea Pigs
MH  - Humans
MH  - Lymph Nodes/immunology
MH  - Peer Review, Research
MH  - Toxicity Tests/*methods
MH  - United States
EDAT- 1999/11/11 00:00
MHDA- 1999/11/11 00:01
CRDT- 1999/11/11 00:00
PHST- 1999/11/11 00:00 [pubmed]
PHST- 1999/11/11 00:01 [medline]
PHST- 1999/11/11 00:00 [entrez]
PST - ppublish
SO  - Fed Regist. 1999 Mar 23;64(55):14006-7.