PMID- 10565680
OWN - NLM
STAT- MEDLINE
DCOM- 19991202
LR  - 20191103
IS  - 1052-9551 (Print)
IS  - 1052-9551 (Linking)
VI  - 8
IP  - 3
DP  - 1999 Sep
TI  - Review: multiple endocrine neoplasia type 1, sporadic neuroendocrine tumors, and 
      MENIN.
PG  - 107-12
AB  - Since the identification and cloning of the gene responsible for the inherited 
      syndrome multiple endocrine neoplasia type 1 (MEN1) in 1997, important advances 
      in the understanding of the disease, the encoded protein (MENIN) and its role in 
      the development of sporadic neuroendocrine and other neoplasms have been made. In 
      this review, the most important recently published data on the pathology of the 
      MEN1 syndrome, alterations of the MEN1 gene in affected families, and sporadic 
      neuroendocrine tumors and the possible function of MENIN will be summarized.
FAU - Komminoth, P
AU  - Komminoth P
AD  - Department of Pathology, University of Zurich, Switzerland.
LA  - eng
PT  - Journal Article
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PT  - Review
PL  - United States
TA  - Diagn Mol Pathol
JT  - Diagnostic molecular pathology : the American journal of surgical pathology, part 
      B
JID - 9204924
RN  - 0 (MEN1 protein, human)
RN  - 0 (Neoplasm Proteins)
RN  - 0 (Proto-Oncogene Proteins)
SB  - IM
MH  - Humans
MH  - Multiple Endocrine Neoplasia
MH  - Multiple Endocrine Neoplasia Type 1/*genetics/*pathology
MH  - Mutation
MH  - Neoplasm Proteins/*genetics/metabolism
MH  - Neuroendocrine Tumors/*genetics/*pathology
MH  - *Proto-Oncogene Proteins
RF  - 71
EDAT- 1999/11/24 00:00
MHDA- 1999/11/24 00:01
CRDT- 1999/11/24 00:00
PHST- 1999/11/24 00:00 [pubmed]
PHST- 1999/11/24 00:01 [medline]
PHST- 1999/11/24 00:00 [entrez]
AID - 10.1097/00019606-199909000-00001 [doi]
PST - ppublish
SO  - Diagn Mol Pathol. 1999 Sep;8(3):107-12. doi: 10.1097/00019606-199909000-00001.