PMID- 10583468
OWN - NLM
STAT- MEDLINE
DCOM- 19991228
LR  - 20220316
IS  - 0953-816X (Print)
IS  - 0953-816X (Linking)
VI  - 11
IP  - 11
DP  - 1999 Nov
TI  - Differential projections from the anterior and posterior divisions of the 
      accessory olfactory bulb to the medial amygdala in the opossum, Monodelphis 
      domestica.
PG  - 3789-99
AB  - The vomeronasal sensory epithelium of mammals contains apical and basal cell 
      populations expressing different G proteins and putative pheromone receptors, 
      which project, respectively, to the anterior and posterior divisions of the 
      accessory olfactory bulb (AOB). In order to analyse whether these segregated 
      pathways are preserved in the connections between the AOB and the amygdala, 
      conjugated dextran-amines were iontophoretically injected into the anterior and 
      posterior divisions of the AOB. We found that efferent projections from both 
      divisions essentially overlap throughout the vomeronasal recipient amygdala. In 
      the medial amygdaloid complex, both divisions project to lamina 1A of layer 1 of 
      the anterodorsal, anteroventral, posterodorsal and posteroventral nuclei. The 
      posterior division alone, however, projects to lamina 1B and layers 2 and 3 of 
      the anterodorsal, anteroventral and posteroventral nuclei. These results 
      constitute a link between molecular, anatomical and functional approaches on the 
      study of the vomeronasal system. Molecular and functional studies support that 
      the two segregated pathways between the vomeronasal organ and the AOB are 
      functionally different. Similarly, the anatomical approaches to the further 
      connections of this system indicate that the medial amygdala possesses ventral 
      and dorsal divisions that are hodologically and functionally different. The 
      present results demonstrate a differential projection from the posterior AOB to 
      the ventral division of the medial amygdala. These findings indicate that the 
      segregated pathways of the vomeronasal system continue to the level of the 
      amygdala, and they provide some clues about the functional implications.
FAU - Martinez-Marcos, A
AU  - Martinez-Marcos A
AD  - Department of Anatomy, Health Science Center at Brooklyn, Sate University of New 
      York, Brooklyn, 11203, USA.
FAU - Halpern, M
AU  - Halpern M
LA  - eng
GR  - DC02745/DC/NIDCD NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - France
TA  - Eur J Neurosci
JT  - The European journal of neuroscience
JID - 8918110
RN  - 0 (Dextrans)
RN  - 0 (Fluorescent Dyes)
RN  - 0 (biotinylated dextran amine)
RN  - 6SO6U10H04 (Biotin)
SB  - IM
MH  - Amygdala/*anatomy & histology/physiology
MH  - Animals
MH  - Axonal Transport
MH  - Biotin/analogs & derivatives
MH  - Chemoreceptor Cells/physiology
MH  - Dextrans
MH  - Efferent Pathways/anatomy & histology
MH  - Female
MH  - Fluorescent Dyes
MH  - Male
MH  - Olfactory Bulb/*anatomy & histology/physiology
MH  - Olfactory Pathways/anatomy & histology/physiology
MH  - Opossums/*anatomy & histology
MH  - Vomeronasal Organ/*innervation
EDAT- 1999/12/03 00:00
MHDA- 1999/12/03 00:01
CRDT- 1999/12/03 00:00
PHST- 1999/12/03 00:00 [pubmed]
PHST- 1999/12/03 00:01 [medline]
PHST- 1999/12/03 00:00 [entrez]
AID - ejn797 [pii]
AID - 10.1046/j.1460-9568.1999.00797.x [doi]
PST - ppublish
SO  - Eur J Neurosci. 1999 Nov;11(11):3789-99. doi: 10.1046/j.1460-9568.1999.00797.x.