PMID- 10587305
OWN - NLM
STAT- MEDLINE
DCOM- 19991215
LR  - 20190831
IS  - 0165-2427 (Print)
IS  - 0165-2427 (Linking)
VI  - 71
IP  - 3-4
DP  - 1999 Nov 30
TI  - Changes in macrophage and lymphocyte subpopulations of lymphoid tissues from pigs 
      infected with the porcine reproductive and respiratory syndrome virus (PRRSV).
PG  - 257-62
AB  - We used an immunohistochemical method to investigate changes in macrophage and 
      lymphocyte subpopulations in various lymphoid tissues of pigs in the acute phase 
      of porcine reproductive and respiratory syndrome virus (PRRSV) infection. The 
      numbers of CD8+ cells and B-cells varied among lymphoid tissues after PRRSV 
      infection. In the infected pigs, numbers of CD8+ cells increased in systemic 
      lymphoid tissues whereas numbers of B-cells increased in mucosa-associated 
      lymphoid tissues. There was no difference in the distribution of virus-infected 
      cells and macrophages between lymphoid tissues of the infected pigs. These 
      changes may be associated with the establishment of virus persistence or the 
      emergence of concurrent infection in mucosal organs.
FAU - Kawashima, K
AU  - Kawashima K
AD  - Department of Pathology, National Institute of Animal Health, Tsukuba, Ibaraki, 
      Japan. kawaken@niah.affrc.go.jp
FAU - Narita, M
AU  - Narita M
FAU - Yamada, S
AU  - Yamada S
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Vet Immunol Immunopathol
JT  - Veterinary immunology and immunopathology
JID - 8002006
RN  - 0 (Antigens, Viral)
SB  - IM
MH  - Animals
MH  - Antigens, Viral/analysis
MH  - Immunohistochemistry
MH  - Lymphoid Tissue/*immunology
MH  - Macrophages/*physiology
MH  - Porcine Reproductive and Respiratory Syndrome/*immunology/pathology
MH  - Swine
MH  - T-Lymphocyte Subsets/*physiology
EDAT- 1999/12/10 00:00
MHDA- 1999/12/10 00:01
CRDT- 1999/12/10 00:00
PHST- 1999/12/10 00:00 [pubmed]
PHST- 1999/12/10 00:01 [medline]
PHST- 1999/12/10 00:00 [entrez]
AID - S0165-2427(99)00102-6 [pii]
AID - 10.1016/s0165-2427(99)00102-6 [doi]
PST - ppublish
SO  - Vet Immunol Immunopathol. 1999 Nov 30;71(3-4):257-62. doi: 
      10.1016/s0165-2427(99)00102-6.