PMID- 10590433
OWN - NLM
STAT- MEDLINE
DCOM- 20000330
LR  - 20061115
IS  - 0197-3851 (Print)
IS  - 0197-3851 (Linking)
VI  - 19
IP  - 12
DP  - 1999 Dec
TI  - Analysis of a de novo complex chromosome rearrangement involving chromosomes 4, 
      11, 12 and 13 and eight breakpoints by conventional cytogenetic, fluorescence in 
      situ hybridization and spectral karyotyping.
PG  - 1143-9
AB  - A complex chromosome rearrangement (CCR) with eight breakpoints resulting in four 
      derivative chromosomes (4, 11, 12 and 13) was detected prenatally in a male fetus 
      of a twin pregnancy. The karyotype of the female second fetus was normal. The 
      apparently balanced de novo CCR was identified by classical cytogenetic methods 
      and fluorescence in situ hybridization (FISH). We compared these findings with 
      results from spectral karyotyping (SKY).
CI  - Copyright 1999 John Wiley & Sons, Ltd.
FAU - Peschka, B
AU  - Peschka B
AD  - Institute of Human Genetics, University of Bonn, Bonn, Germany.
FAU - Leygraaf, J
AU  - Leygraaf J
FAU - Hansmann, D
AU  - Hansmann D
FAU - Hansmann, M
AU  - Hansmann M
FAU - Schrock, E
AU  - Schrock E
FAU - Ried, T
AU  - Ried T
FAU - Engels, H
AU  - Engels H
FAU - Schwanitz, G
AU  - Schwanitz G
FAU - Schubert, R
AU  - Schubert R
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - England
TA  - Prenat Diagn
JT  - Prenatal diagnosis
JID - 8106540
SB  - IM
MH  - Abortion, Eugenic
MH  - Adult
MH  - Chromosome Aberrations/*genetics
MH  - *Chromosomes, Human, Pair 11
MH  - *Chromosomes, Human, Pair 12
MH  - *Chromosomes, Human, Pair 13
MH  - *Chromosomes, Human, Pair 4
MH  - Diagnosis, Differential
MH  - Diseases in Twins/embryology/*genetics
MH  - Female
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Karyotyping
MH  - Male
MH  - Pregnancy
MH  - Pregnancy, Multiple
MH  - Twins
MH  - Ultrasonography, Prenatal
RF  - 25
EDAT- 1999/12/11 09:00
MHDA- 2000/04/01 09:00
CRDT- 1999/12/11 09:00
PHST- 1999/12/11 09:00 [pubmed]
PHST- 2000/04/01 09:00 [medline]
PHST- 1999/12/11 09:00 [entrez]
AID - 10.1002/(SICI)1097-0223(199912)19:12<1143::AID-PD730>3.0.CO;2-9 [pii]
PST - ppublish
SO  - Prenat Diagn. 1999 Dec;19(12):1143-9.