PMID- 10639620
OWN - NLM
STAT- MEDLINE
DCOM- 20000210
LR  - 20190915
IS  - 0148-639X (Print)
IS  - 0148-639X (Linking)
VI  - 23
IP  - 2
DP  - 2000 Feb
TI  - Quantitative analysis of reflex inhibition in single motor units in human 
      masseter muscle: effects of stimulus intensity.
PG  - 259-66
AB  - Inhibitory reflex responses to electrical stimulation of the mental nerve were 
      studied in recordings from single motor units (SMU) in the human masseter muscle. 
      A new analytical technique for spike train data was used. Electrical stimuli were 
      delivered to the mental nerve when the SMU fired with two consecutive inter-spike 
      intervals (ISIs) within the range of 90 ms to 110 ms. Stimuli were delivered with 
      increasing stimulus delays after the preceding SMU action potential (AP). Sham, 
      non-painful, and painful stimulus intensities were applied. The post-stimulus 
      firing probability of the SMU was progressively decreased among the three 
      conditions. Analysis of the relation between stimulus delays and ISI for the 
      first post-stimulus APs revealed a linear relation which was shifted upward, and 
      the slope was increased with increasing stimulus intensity. This may be explained 
      by a differential effect of the increasing stimulus intensity on the duration and 
      amplitude of the inhibitory post-synaptic potential. The methods used in the 
      present study provide a useful means of quantifying the effects of motoneuron 
      excitability in detail.
CI  - Copyright 2000 John Wiley & Sons, Inc.
FAU - Graven-Nielsen, T
AU  - Graven-Nielsen T
AD  - Center for Sensory-Motor Interaction, Laboratory for Experimental Pain Research, 
      Aalborg University, Fredrik Bajers Vej 7D-3, DK-9220 Aalborg E, Denmark. 
      tgn@miba.auc.dk
FAU - Svensson, P
AU  - Svensson P
FAU - McMillan, A S
AU  - McMillan AS
FAU - Arendt-Nielsen, L
AU  - Arendt-Nielsen L
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Muscle Nerve
JT  - Muscle & nerve
JID - 7803146
SB  - IM
MH  - Adult
MH  - Electric Stimulation
MH  - Electrodes
MH  - Electromyography
MH  - Humans
MH  - Male
MH  - Masseter Muscle/cytology/innervation/*physiology
MH  - Motor Neurons/*physiology
MH  - Pain/physiopathology
MH  - Reflex/*physiology
MH  - Regression Analysis
EDAT- 2000/01/20 00:00
MHDA- 2000/01/20 00:01
CRDT- 2000/01/20 00:00
PHST- 2000/01/20 00:00 [pubmed]
PHST- 2000/01/20 00:01 [medline]
PHST- 2000/01/20 00:00 [entrez]
AID - 10.1002/(SICI)1097-4598(200002)23:2<259::AID-MUS18>3.0.CO;2-F [pii]
AID - 10.1002/(sici)1097-4598(200002)23:2<259::aid-mus18>3.0.co;2-f [doi]
PST - ppublish
SO  - Muscle Nerve. 2000 Feb;23(2):259-66. doi: 
      10.1002/(sici)1097-4598(200002)23:2<259::aid-mus18>3.0.co;2-f.