PMID- 10645714
OWN - NLM
STAT- MEDLINE
DCOM- 20000203
LR  - 20091021
IS  - 0030-6002 (Print)
IS  - 0030-6002 (Linking)
VI  - 140
IP  - 48
DP  - 1999 Nov 28
TI  - [Dual fluorescence in situ hybridization analysis of synovial sarcoma].
PG  - 2691-4
AB  - Synovial sarcoma have (about in 95% of the cases) the specific and characteristic 
      reciprocal chromosomal translocation t(X; 18) (p11.2; q 11.2). Application of 
      dual-colour fluorescence in situ hybridization (FISH) on interphase nuclei to 
      identify the specific translocation has a diagnostic importance for daily 
      pathological practice. For visualisation of the translocated chromosomal 
      fragments of synovial sarcoma cells on imprint smears, chromosome X painting 
      probes and chromosome 18 centromeric probes were used. Our present study 
      indicates that the precise preoperative diagnosis of synovial sarcoma using 
      dual-colour FISH is possible on smears and this possibility (to identify specific 
      chromosomal translocations in soft tissue tumours) is a landmark in the 
      preoperative diagnosis of soft tissue sarcomas.
FAU - Sapi, Z
AU  - Sapi Z
AD  - Pathologiai Osztaly, Haynal Imre Egeszsegtudomanyi Egyetem, Onkopathologiai es 
      Citodiagnosztikai Tanszek, Budapest.
FAU - Antal, I
AU  - Antal I
FAU - Turi, A
AU  - Turi A
FAU - Szendroi, M
AU  - Szendroi M
FAU - Bodo, M
AU  - Bodo M
LA  - hun
PT  - Case Reports
PT  - English Abstract
PT  - Journal Article
TT  - Synovalis sarcoma kettos jelolesu fluorescens in situ hibridizacios vizsgalata.
PL  - Hungary
TA  - Orv Hetil
JT  - Orvosi hetilap
JID - 0376412
SB  - IM
MH  - Adult
MH  - Fingers
MH  - Foot
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Male
MH  - Middle Aged
MH  - Sarcoma, Synovial/*diagnosis/genetics/pathology/surgery
MH  - Soft Tissue Neoplasms/diagnosis/genetics/pathology/surgery
MH  - Translocation, Genetic
EDAT- 2000/01/25 00:00
MHDA- 2000/01/25 00:01
CRDT- 2000/01/25 00:00
PHST- 2000/01/25 00:00 [pubmed]
PHST- 2000/01/25 00:01 [medline]
PHST- 2000/01/25 00:00 [entrez]
PST - ppublish
SO  - Orv Hetil. 1999 Nov 28;140(48):2691-4.