PMID- 10648152
OWN - NLM
STAT- MEDLINE
DCOM- 20000328
LR  - 20071114
IS  - 1090-7807 (Print)
IS  - 1090-7807 (Linking)
VI  - 142
IP  - 2
DP  - 2000 Feb
TI  - Time-domain quantification of multiple-quantum-filtered (23)Na signal using 
      continuous wavelet transform analysis.
PG  - 341-7
AB  - The application of continuous wavelet transform (CWT) analysis technique is 
      presented to analyze multiple-quantum-filtered (MQF) (23)Na magnetic resonance 
      spectroscopy (MRS) data. CWT acts on the free-induction-decay (FID) signal as a 
      time-frequency variable filter. The signal-to-noise ratio (SNR) and frequency 
      resolution of the output filter are locally increased. As a result, MQF 
      equilibrium longitudinal magnetization and the apparent fast and slow transverse 
      relaxation times are accurately estimated. A developed iterative algorithm based 
      on frequency signal detection and components extraction, already proposed, was 
      used to estimate the values of the signal parameters by analyzing simulated 
      time-domain MQF signals and data from an agarose gel. The results obtained were 
      compared to those obtained by measurement of signal height in frequency domain as 
      a function of MQF preparation time and those obtained by a simple time-domain 
      curve fitting. The comparison indicates that the CWT approach provides better 
      results than the other tested methods that are generally used for MQF (23)Na MRS 
      data analysis, especially when the SNR is low. The mean error on the estimated 
      values of the amplitude signal and the apparent fast and slow transverse 
      relaxation times for the simulated data were 2.19, 6. 63, and 16.17% for CWT, 
      signal height in frequency domain, and time-domain curve fitting methods, 
      respectively. Another major advantage of the proposed technique is that it allows 
      quantification of MQF (23)Na signal from a single FID and, thus, reduces the 
      experiment time dramatically.
CI  - Copyright 2000 Academic Press.
FAU - Serrai, H
AU  - Serrai H
AD  - Department of Radiology, University of Pennsylvania School of Medicine, 
      Philadelphia, Pennsylvania 19104-6100, USA.
FAU - Borthakur, A
AU  - Borthakur A
FAU - Senhadji, L
AU  - Senhadji L
FAU - Reddy, R
AU  - Reddy R
FAU - Bansal, N
AU  - Bansal N
LA  - eng
GR  - AR45242/AR/NIAMS NIH HHS/United States
GR  - HL-54574/HL/NHLBI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - J Magn Reson
JT  - Journal of magnetic resonance (San Diego, Calif. : 1997)
JID - 9707935
RN  - 0 (Sodium Isotopes)
SB  - IM
MH  - Magnetic Resonance Spectroscopy/*methods
MH  - Sodium Isotopes
EDAT- 2000/01/29 09:00
MHDA- 2000/04/01 09:00
CRDT- 2000/01/29 09:00
PHST- 2000/01/29 09:00 [pubmed]
PHST- 2000/04/01 09:00 [medline]
PHST- 2000/01/29 09:00 [entrez]
AID - S1090-7807(99)91947-X [pii]
AID - 10.1006/jmre.1999.1947 [doi]
PST - ppublish
SO  - J Magn Reson. 2000 Feb;142(2):341-7. doi: 10.1006/jmre.1999.1947.