PMID- 10651204
OWN - NLM
STAT- MEDLINE
DCOM- 20000214
LR  - 20190817
IS  - 0047-1828 (Print)
IS  - 0047-1828 (Linking)
VI  - 64
IP  - 1
DP  - 2000 Jan
TI  - Age-adjusted heart rate variability as an index of the severity and prognosis of 
      heart failure.
PG  - 32-8
AB  - The age-adjusted, heart rate variability (HRV) was evaluated as a parameter for 
      the severity of heart failure and its prognosis. HRV was obtained by 24-h Holter 
      monitoring in patients with left ventricular dysfunction (LVD). New York Heart 
      Association (NYHA) functional classification, echocardiography, radioisotope 
      ventriculography, and blood examination were performed, and compared between 
      patients and normal subjects. The evaluation was repeated during the follow-up 
      period. Finally, using the lower limit of HRV, patients were divided into either 
      normal or abnormal group for each low-frequency power (LF) and high-frequency 
      power (HF) (age-adjusted HRV). Other parameters of heart failure and prognosis 
      were compared between these 2 groups. HRV tended to be lower in patients with 
      LVD. HF decreased at the early stage of heart failure, but did not decrease 
      progressively. LF decreased progressively. HRV change paralleled the change of 
      NYHA. The abnormal HRV group showed a poor prognosis for cardiac death, but not 
      for sudden cardiac death. In patients with LVD, HRV was decreased compared with 
      the normal subjects. Change in HRV correlated with the change in NYHA 
      classification. Age-adjusted HRV correlated with cardiac-death prognosis, but not 
      for sudden cardiac death.
FAU - Soejima, K
AU  - Soejima K
AD  - Department of Internal Medicine, Keio University School of Medicine, Tokyo, 
      Japan. ksoejima@bics.bwh.harvard.edu
FAU - Akaishi, M
AU  - Akaishi M
FAU - Meguro, T
AU  - Meguro T
FAU - Oyamada, K
AU  - Oyamada K
FAU - Yoshikawa, T
AU  - Yoshikawa T
FAU - Mitamura, H
AU  - Mitamura H
FAU - Ogawa, S
AU  - Ogawa S
LA  - eng
PT  - Journal Article
PL  - Japan
TA  - Jpn Circ J
JT  - Japanese circulation journal
JID - 7806868
SB  - IM
MH  - Aged
MH  - Cardiomyopathy, Dilated/*physiopathology
MH  - Cause of Death
MH  - Death, Sudden, Cardiac
MH  - Electrocardiography, Ambulatory
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Failure/mortality/*physiopathology
MH  - Heart Rate/*physiology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/physiopathology
MH  - Prognosis
MH  - Reference Values
MH  - Regression Analysis
MH  - Severity of Illness Index
MH  - Time Factors
MH  - Ventricular Dysfunction, Left/*physiopathology
EDAT- 2000/01/29 09:00
MHDA- 2000/02/19 09:00
CRDT- 2000/01/29 09:00
PHST- 2000/01/29 09:00 [pubmed]
PHST- 2000/02/19 09:00 [medline]
PHST- 2000/01/29 09:00 [entrez]
AID - 10.1253/jcj.64.32 [doi]
PST - ppublish
SO  - Jpn Circ J. 2000 Jan;64(1):32-8. doi: 10.1253/jcj.64.32.